New Brain Implant Device Could Restore Function in Paralyzed Limbs

University of Cambridge Department of Engineering and Clinical Neurosciences

A brain implant that can restore arm and leg movements has been developed by British scientists to boost connections between neurons and the paralyzed limbs, offering hope to accident victims.

The device combines flexible electronics and human stem cells – the body’s ‘reprogrammable’ master cells – to better integrate with the nerve and drive limb function.

Previous attempts at using neural implants to restore limb function have mostly failed, as scar tissue tends to form around the electrodes over time, impeding the connection between the device and the nerve. By sandwiching a layer of muscle cells reprogrammed from stem cells between the electrodes and the living tissue in rats, the researchers found that the device integrated with the host’s body and the formation of scar tissue was prevented.

The cells survived on the electrode for the duration of the 28-day experiment, the first time this has been monitored over such a long period.

The researchers say that by combining two advanced therapies for nerve regeneration – cell therapy and bioelectronics – into a single device, they can overcome the shortcomings of both approaches, improving functionality and sensitivity.

“This was a high-risk endeavor, and I’m so pleased that it worked,” said Professor George Malliaras from Cambridge’s Department of Engineering, who co-led the research. “It’s one of those things that you don’t know whether it will take two years or ten before it works, and it ended up happening very efficiently.”

CHECK OUT: Movement in Paralyzed Arms is Restored by ‘Zapping’ Spinal Cords With Electrical Stimulation

“This interface could revolutionize the way we interact with technology,” said co-first author Amy Rochford, who worked on the professor’s team. “By combining living human cells with bioelectronic materials, we’ve created a system that can communicate with the brain in a more natural and intuitive way, opening up new possibilities for prosthetics, brain-machine interfaces, and even enhancing cognitive abilities.”

While extensive research and testing will be needed before it can be used in humans, the device is a promising development for amputees or those who’ve lost function in limbs. The results were reported this month in the journal Science Advances.

A huge challenge when attempting to reverse such injuries is the inability of neurons to regenerate and rebuild disrupted neural circuits.

“If someone has an arm or a leg amputated, for example, all the signals in the nervous system are still there, even though the physical limb is gone,” said Dr. Damiano Barone from Cambridge’s Department of Clinical Neurosciences, who co-led the research. “The challenge with integrating artificial limbs, or restoring function to arms or legs, is extracting the information from the nerve and getting it to the limb so that function is restored.”

LOOK: See Incredible Transformation of Paralyzed Mice Given Nanofibers in 4 Week Study Breakthrough

One way of addressing this problem is implanting a nerve in the large muscles of the shoulder and attaching electrodes to it. The problem with this approach is scar tissue forms around the electrode, plus it is only possible to extract surface-level information from the electrode.

To get better resolution, any implant for restoring function would need to extract much more information from the electrodes. And to improve sensitivity, the researchers wanted to design something that could work on the scale of a single nerve fibre, or axon.

“An axon itself has a tiny voltage,” said Barone. “But once it connects with a muscle cell, which has a much higher voltage, the signal from the muscle cell is easier to extract. That’s where you can increase the sensitivity of the implant.”

The researchers designed a biocompatible flexible electronic device that is thin enough to be attached to the end of a nerve. A layer of stem cells, reprogrammed into muscle cells, was then placed on the electrode. This is the first time that this type of stem cell, called an induced pluripotent stem cell, has been used in a living organism in this way.

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“These cells give us an enormous degree of control,” said Barone. “We can tell them how to behave and check on them throughout the experiment. By putting cells in between the electronics and the living body, the body doesn’t see the electrodes, it just sees the cells, so scar tissue isn’t generated.”

The Cambridge biohybrid device was implanted into the paralyzed forearm of the rats. The stem cells, which had been transformed into muscle cells prior to implantation, integrated with the nerves in the rat’s forearm. While the rats did not have movement restored to their forearms, the device was able to pick up the signals from the brain that control movement. If connected to the rest of the nerve or a prosthetic limb, the device could help restore movement.

The cell layer also improved the function of the device, by improving resolution and allowing long-term monitoring inside a living organism. The cells survived through the 28-day experiment: the first time that cells have been shown to survive an extended experiment of this kind.

The researchers say that their approach has multiple advantages over other attempts to restore function in amputees. In addition to its easier integration and long-term stability, the device is small enough that its implantation would only require keyhole surgery. Other neural interfacing technologies for the restoration of function in amputees require complex patient-specific interpretations of cortical activity to be associated with muscle movements, while the Cambridge-developed device is a highly scalable solution since it uses ‘off the shelf’ cells supplied by the University’s Kotter lab, which are owned by synthetic biology company

In addition to its potential for the restoration of function in people who have lost the use of a limb or limbs, the researchers say their device could also be used to control prosthetic limbs by interacting with specific axons responsible for motor control.

“This technology represents an exciting new approach to neural implants, which we hope will unlock new treatments for patients in need,” said co-first author Dr Alejandro Carnicer-Lombarte, also from the Department of Engineering.

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The researchers are now working to further optimize the devices and improve their scalability. The team have filed a patent application with the support of Cambridge Enterprise, the University’s technology transfer arm, which is also supporting the commercialization of the technology.

CONNECT This Breakthrough With Physical Therapists on Social Media…

A 90-Year-old Tortoise Becomes a Father For the First Time With His Partner of 29 Years

Mr. Pickles with baby –Credit: Jackelin Reyna / Houston Zoo

Mr. Pickles, a 90-year-old radiated tortoise and the oldest animal at the Houston Zoo, became a father for the first time last week.

Mr. Pickles and his 53-year-old partner, Mrs. Pickles, welcomed three hatchlings that could live for up to 150 years if well taken care of.

Native to southern Madagascar, radiated tortoises are Critically Endangered and rarely produce offspring, Houston Zoo officials said.

“The new hatchlings came as a surprise when a herpetology keeper happened upon Mrs. Pickles as the tortoise was laying her eggs at closing time,” the Houston Zoo blog reported.

“The animal care team quickly went to work uncovering the eggs and getting them to the safety of the Reptile & Amphibian House. The soil in Houston isn’t hospitable to the Madagascar native tortoises, and it’s unlikely the eggs would have hatched on their own if the keeper hadn’t been in the right place at the right time.”

3 Baby Pickles – Credit: Jackelin Reyna / Houston Zoo

Arriving in 1996, Mrs. Pickles has lived at the Houston Zoo alongside Mr. Pickles ever since. The kids have been named Dill, Gherkin, and Jalapeño.

The new parents have been key to the Association of Zoos and Aquariums Species Survival Plan for this exquisite reptile that has unfortunately fallen afoul of the illegal animal trade.

MORE REPTILE RESCUES: Baby Galápagos Pink Iguanas Seen for the First Time Ever—Offering So Much Hope to Scientists

In 2018 10,000 radiated tortoises were found in a private home in Toliara, Madagascar. Rescuers transported them to Le Village Des Tortues (“Turtle Village”), a private wildlife rehabilitation facility in Ifaty, 18 miles north of Toliara.

Preventative measures for insuring against the extinction of the reptile has been the establishment of breeding colonies on the Reunion Islands and Mauritius where the conditions are similar to its home in Madagascar.

SHARE These Adorable New Parents With Your Friends… 

Critically-Endangered West African Lion Going from Strength to Strength in Niokolo Koba, Senegal

Released by Panthera / Department of National Parks, Senegal, by Kris Everatt

Reprinted with permission from World at Largean independent news outlet covering conflict, travel, science, conservation, and health and fitness.

In a thrilling sign of recovery for the Critically-Endangered West African lion, camera trap footage and photos of a West African lioness and her three cubs playing, nursing, and feeding in Senegal’s Niokolo Koba National Park (NKNP) were released by the conservation outfit Panthera.

The high-definition videos and photos feature Florence, a 9 to 10-year-old GPS-collared lioness that scientists believe has now given birth to three litters, totaling nine cubs, since 2021.

Now considered the matriarch of Niokolo Koba, this lioness has contributed approximately one-third of the park’s lion population which has grown slowly from a razor’s edge pride of 10 to 15 individuals in 2011 to perhaps as many as 40 today.

Just 120-374 West African lions are estimated to remain in the wild today, with their historic range having shrunk by 99%. They are part of the Northern lion subspecies, which used to range across North Africa.

When WaL reported on NKNP’s lions last year, Panthera West and Central Africa Regional Director Dr. Philipp Henschel said that the lions had hunkered down in a tiny core area, about 10% of the park’s massive 9,000 square kilometers.

Since then, the lions have become more adventurous, and have slowly been exiting that core.

“We covered the entire park in camera traps last year and that also provided evidence of lions in areas where we didn’t know resident lions existed,” Dr. Henschel told WaL on Wednesday. “And so overall if we add that up we’re at about over a third, so about 35% or so of the park occupied by lions and it might be more, it’s not always a given that you’ll detect them”.

Lions being pride animals, some of this territorial expansion seems to be the early stages in the creation of new prides, since the camera trap arrays have picked up a coalition of pride-less males roaming around the park, all of whom might be Florence’s offspring.

“These animals we detect ranging quite widely out of this core area, and now we’ve also picked up a number of females leaving this core area,” says Dr. Henschel. “As these lions fill in the landscape the females breed and this leads to the establishment of new prides in new areas that we’re currently documenting”.

Lions at one of the road crossings in the park – Panthera, Department of National Parks, Senegal, by Kris Everatt

Against all odds

Henschel and his colleagues from Panthera arrived in Senegal’s largest national park, and the second-largest in West Africa, in 2011 when the situation was dire and uncertain.

Along with a “commendable” team of under-equipped rangers, they managed to collar Florence in the dead of night last year.

“They were never collared before so we know almost nothing about these cats,” Henschel told WaL a year ago in May.

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“They were never seen. Back in the days in 2011 when we did the first survey there, I had a team of 4 people all part of the park’s staff, and of them, nobody had ever seen a lion. One of them, a driver, had already worked in the park for 10 years; he had never seen a lion”.

Now the work of restoring the lion populations is going about as well as anyone could have dared hope for. There’s much more interest from the government, which has been able to finance, train, and maintain 3 armed ranger squads that last year covered almost 9,000 kilometers of ground on their patrols, or about 35% of the park on foot.

There’s a commitment from the Park’s lead conservator who has given the green light to equip and hire 3 more ranger teams, which Henschel describes as “no small feat for the government,” which pays for real paramilitary training, and “a good salary”.

Perhaps the largest danger to the lions now is a population bottleneck, something that just comes with the territory when restoring a species from such a tiny number.

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However, even here there is good news.

“Even when I carried out the first ever lion surveys in 2011, I did intensive searches for lion scats, lion droppings, and we already have a snapshot from 2011 when the population was extremely low at 10-15 animals, and it still looked alright,” said Dr. Henschel.

“The geneticist reassured me that the genetic diversity was still quite high and that with a possible recent collapse of the lion population but [sic] that still has intrinsic diversity within it”.

“When the geneticists looked at the lion genetics, what they found was the Senegal population contains haplotypes that cannot be found in any other lion population in the world. So these are really unique to the Senegal population. Ideally, we would leave this genetic unit intact, but it depends on the results of our genetic analysis,” said Dr. Henschel.

MORE LION NEWS: Lions in India Get New Sanctuary as Numbers of Asiatic Lions Soar in Their Last Stronghold

The analysis is expected next year, but the central government and parks department are keen to take advantage of the lions for tourism revenue. The park is truly enormous; the same size as Yellowstone in the US, and contains other rare species like leopards, and the only remaining population of West African wild dogs.

“Compared to when we started the lions are so much more visible,” says Dr. Henschel. “There’s a new lodge in the park. I spoke to the lodge manager last month and they’re now fully booked for the game viewing season, and things are moving in that direction”.

SHARE This Unbelievable Recovery With Your Own Pride… 

Renovation Unearths Paintings Behind Kitchen Walls Nearly 400-Years-old

Released by Luke Budworth

In York, a seemingly normal apartment was hiding a historic secret for centuries until a kitchen remodeling exposed it to the light of day.

29-year-old Luke Budworth received a call from the men putting a new kitchen into his apartment. It read “did you know there was a painting behind here?”

It wasn’t a painting, nor a bit of leftover Victorian wallpaper as Budworth had originally suspected, but rather a frieze dating back hundreds of years ago depicting a Biblical scene

The kitchen remodeling was finished before Budworth could see for himself, but after doing a little investigation in the open-plan living space he discovered another frieze. He contacted Historic England, the largest historical preservation society in the country, to see if they were able to make sense of the discovery.

Over time, Budworth came to learn that York had once been encircled by a wall, and his second-floor apartment was built using some of this wall. The ground floor is taken up by a cafe and charity bookshop which is listed as being a Grade II Georgian building from 1747.

released by Luke Budworth

Yet his discovery dates even further back. Historic England gave him and his partner a full-size replica of the frieze to hang on the wall, and Budworth used the Biblical imagery as a reference and managed to find a picture exceedingly similar from a book called Emblems written in 1635 written by the poet Francis Quarles.

MORE LOST ART: Artwork Found in Shed Covered in Bird Droppings Turns Out to be Early Van Dyck Now at Auction for $3 Million

Historic England explained that pictures such as those in the frieze fell out of fashion by the year 1700, so the work was done between those two dates, potentially placing it nearly 400 years old.

“They raise various questions about the ages of the buildings in this row of historic homes and the history of Micklegate itself,” Historic England told CNN. “Finds like this tell us that our historic homes have many secrets and we’ve been pleased to work with this homeowner on looking after these murals for the future.”

HAVE You Ever Stumbled Upon A Bit Of History Before? Tell Us In The Comments Below…

Why Crashing Banks Will Usher in Digital Currency

  • Three large banks failed in a single week in March 2023, and the ripple effect could easily take down the entire banking system. The cascading bank failures began March 8 with the shut down and liquidation of the crypto bank Silvergate Capital. It had invested deposits in Treasury bonds, which lost value as interest rates were hiked to stem inflation

  • March 10, Silicon Valley Bank (SVB) failed. It too was invested in government bonds, which again became a problem when customers began making large fear-based withdrawals. This was the second largest bank failure in U.S. history, and the largest since the financial crisis in 2008

  • Spooked by the failure of Silicon Valley Bank, Signature Bank customers withdrew more than $10 billion in the days that followed, resulting in the shutdown of Signature Bank on March 12

  • Government regulators have promised to make customers of the two banks “whole” by insuring all funds, not just the first $250,000. Only select “too big to fail” banks will be eligible for this kind of special treatment. Small local banks will not be eligible

  • The most likely outcome of this bailout system is a consolidation of banks until we’re left with just a small number of mega-banks. This consolidation, in turn, will facilitate the rollout of a central bank digital currency (CBDC), as the banking industry will be a tight-knit monopoly

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Three large banks failed in a single week in March 2023, and the ripple effect could easily take down the entire banking system, although government officials insist the banking sector “remains strong” and that the problems faced by these banks “do not appear to be widespread.”

The cascading bank failures began March 8 with the shut down and liquidation of the crypto bank Silvergate Capital.

As reported by Government Executive:

“During 2022, Silvergate’s deposit base grew dramatically, almost doubling its assets to $210 billion. But the bank did not have either the administrative capacity or market demand to lend out all of the money, as banks normally do.

So, it invested the excess deposits in Treasury bonds and mortgage investment products. But the bond purchases became a problem as the Federal Reserve began to raise interest rates to address inflation.”

Two days later, March 10, Silicon Valley Bank (SVB) — the 16th largest bank in the U.S.

— failed. It too was invested in government bonds, which again became a problem when customers began making large fear-based withdrawals. This was the second largest bank failure in U.S. history, and the largest since the financial crisis in 2008.

Allegedly “spooked” by the failure of Silicon Valley Bank, Signature Bank customers then withdrew more than $10 billion, resulting in the shutdown of Signature Bank on March 12, making it the third-largest bank failure in history.

The Federal Deposit Insurance Corp. (FDIC) took control of Silicon Valley Bank and Signature, and government regulators have promised to make all customers “whole” by insuring all funds, not just the first $250,000. In other words, government is bailing out the banking system yet again, on the taxpayers’ dime.

Within a week, Signature was bought up by Flagstar Bank, a subsidiary of New York Community Bancorp (one of the largest banks in the U.S.).

According to the FDIC, anyone who had deposits at Signature Bank will automatically become a client of Flagstar Bank, except for crypto banking clients, as Signature’s digital banking business was not included in Flagstar’s bid.

The FDIC is also left holding $11 billion-worth of “toxic waste debt” in the form of commercial real estate loans for rent-regulated buildings, as this debt portfolio was also rejected by Flagstar.

The FDIC is still looking for a buyer for Silicon Valley Bank.

President Joe Biden’s comments shortly after the three bank failures was that “Americans can have confidence that the banking system is safe” and that “Your deposits will be there when you need them.” Treasury Secretary Janet Yellen also insists the U.S. banking system “remains sound.”

Should we believe them? Probably not. Within days of those statements, the contagion had already spread to Credit Suisse, the largest bank in Switzerland. After government initially stepped in to cover some of the losses, the Swiss banking giant was sold to the UBS Group.

The acquisition was announced March 19.

It’s hard to believe the ripple effects of bank failures of this magnitude can really be stopped. The question is, should we even try? As reported by Government Executive,

government has no obligation to step in and bail these banks out under current banking regulations.

What’s more, the biased bailout system now being put into place will virtually guarantee further bank consolidations and the widespread rollout of a central bank digital currency (CBDC). As reported by Newsweek March 16, 2023:

“During a Senate Finance Committee hearing, Yellen was grilled by Oklahoma GOP Senator James Lankford over the Biden administration’s handling of the banking crisis, which saw the federal government offer a multibillion-dollar bailout to Silicon Valley Bank (SVB) after a bank run left it without enough cash to back up hundreds of millions of dollars of its clients’ deposits. Most of those deposits were not insured.

To address the crisis, U.S. bank regulators announced a plan last weekend to fully insure all deposits at SVB as well as the crypto-friendly Signature Bank.

This would cover all deposits above the Federal Deposit Insurance Corp.’s insured limit of $250,000. Federal officials said the plan would be paid for by a special fee levied on all FDIC institutions.

While all banks would be required to pay for the plan, Yellen said under questioning Thursday that it would not apply to every bank. She said the federal government would extend the privilege only to troubled banks whose failure would have a profound impact on the U.S. financial system.

Uninsured deposits, Yellen said, would be covered only if a ‘failure to protect uninsured depositors would create systemic risk and significant economic and financial consequences,’ which would be decided by a supermajority of the FDIC’s board members, Yellen, and the President …

In further questioning, Lankford asked Yellen whether that policy’s implication would be that small banks would become less appealing to depositors with accounts exceeding the FDIC’s $250,000 insurance threshold …

Amid the sharp increase in bank mergers over the past decade, Lankford expressed concern that the trend could only accelerate under current policy, causing the U.S. banking system to become less resilient.

“I’m concerned you’re … encouraging anyone who has a large deposit at a community bank to [hear], ‘We’re not going to make you whole, but if you go to one of our preferred banks, we will make you whole,'” Lankford told Yellen. Yellen replied, ‘That’s certainly not something that we’re encouraging.'”

And yet that’s exactly what this policy will be encouraging. Actions speak louder than words, and in this case, the outcome of this policy is quite clear, regardless of what Yellen is saying.

To recap, the FDIC will only insure deposits up to $250,000 if your money is in a small bank, but if your money is in a big bank, uninsured deposits over that amount will be covered as well, should the bank fail.

Adding insult to injury, while the system is clearly biased and won’t protect everyone, all banks (and hence account holders) will be forced to pay this “special fee” to the FDIC that will, supposedly, insure all these uninsured deposits at preferred banks.

The most likely outcome of this bailout system is a consolidation of banks until we’re left with just a small number of mega-banks. We’re already starting to see the early phases of this, with “the big three” — Bank of America, Citigroup and Wells Fargo — reporting

a deposit spike in the wake of the SVB collapse and Yellen’s announcement that only certain preferred banks will be covered above FDIC insurance limits.

This consolidation, in turn, will facilitate the rollout of a central bank digital currency (CBDC), as the banking industry will be a very tight-knit monopoly. Let’s say there are only half a dozen banks in all of America. All they have to do is make the switch to CBDC as a group, and anyone with a bank account in America will be automatically trapped in the new system. As reported by News Punch:

“What we are seeing is a push towards Global Government that is being camouflaged and cloaked in humanitarianism, multiculturalism, as well as manufactured threats such as global warming and pandemics in order to condition the population into accepting globalization and a One World Government.

In order for this to occur the elite are planning to create a global financial crisis the likes of which the world has never seen. Out of the ashes of this financial crisis will rise the phoenix of is a New International Economic Order. The public will be told that the new order is the only way to stabilize the world economy and save what little remains of their wealth …

People often ask why the globalist elite would collapse the world economy. Wouldn’t that mean they destroy their own wealth in the process? The answer is no. The elite have been consolidating their wealth in order to protect it for centuries … When the world financial system finally crashes the elite will be positioned to buy what’s left for pennies on the dollar.

Where does this leave the rest of the world financially? The answer is in bondage to a Techno-Communist World Governmental System led by the World Economic Forum in Davos and the hidden hands that control the public face of that cabal. If you pay attention now you can see that everything around you is being engineered towards this one goal …

The globalist elite are also forcing their vassal states to move towards centralizing currency in the form of a … CBDC, which by the way, is not currency at all – it is software designed as a tool of total social control … If they can cancel out your bank balance with a single keystroke, then you have no freedom, no autonomy. You are a slave …”

The fact that CBDCs are intended as financial shackles to control you within what amounts to an open-air prison is also noted by South Dakota Gov. Kristi Noem

in the Fox News interview above.

She highlights a proposed Uniform Commercial Code (UCC) update that seeks to redefine “currency” to exclude decentralized crypto currencies, effectively putting the government on the path to a CBDC monopoly. Noem vetoed the bill and is urging other states to reject it as well.

The UCC Code is a set of laws that govern commercial transactions in the U.S. While not a federal law, it’s a set of laws that states agree to adopt in a uniform fashion to facilitate interstate business.

So, it appears they intend to begin the financial takeover by rolling out the CBDC on the state level first, and legislators who believe in freedom must denounce all such plans.

According to News Punch,

the destruction of Silicon Valley Bank was intentional. While I cannot vouch for that, it’s interesting to note that SVB was in relatively good shape before it went kaput overnight.

As explained by the Sovereign Research and Advisory Group in an article titled “If SVB Is Insolvent, So Is Everyone Else,”

the 2008 banking crash occurred because Lehman Brothers and other banks had used depositors’ money to buy extremely risky no-money-down mortgage bonds.

While the economy was good, banks earned hefty profits from these toxic assets, but as soon as the economy downshifted, these toxic securities plunged in value and wiped them out.

This time, however, the toxic asset is not mortgages obtained by people with no job, income or history of paying their bills. No, this time, it’s U.S. government bonds that are sinking banks, and these bonds are supposed to be the safest investment there is. Sovereign Research and Advisory Group writes:

“Silicon Valley Bank was no Lehman Brothers. Whereas Lehman bet almost ALL of its balance sheet on those risky mortgage bonds, SVB actually had a surprisingly conservative balance sheet.

According to the bank’s annual financial statements from December 31 of last year, SVB had $173 billion in customer deposits, yet “only” $74 billion in loans. I know this sounds ridiculous, but banks typically loan out MOST of their depositors’ money.

Wells Fargo, for example, recently reported $1.38 trillion in deposits. $955 billion of that is loaned out. That means Wells Fargo has made loans with nearly 70% of its customer’s money, while SVB had a more conservative ‘loan-to-deposit ratio’ of roughly 42%.

Point is, SVB did not fail because they were making a bunch of high-risk NINJA loans. Far from it. SVB failed because they parked the majority of their depositors’ money ($119.9 billion) in US GOVERNMENT BONDS. This is the really extraordinary part of this drama.

US government bonds are supposed to be the safest, most ‘risk free’ asset in the world. But that’s totally untrue, because even government bonds can lose value. And that’s exactly what happened.

Most of SVB’s portfolio was in long-term government bonds, like 10-year Treasury notes. And these have been extremely volatile. In March 2020, for example, interest rates were so low that the Treasury Department sold some 10-year Treasury notes at yields as low as 0.08%.

But interest rates have increased so much since then; last week the 10-year Treasury yield was more than 4%. And this is an enormous difference.

If you’re not terribly familiar with the bond market, one of the most important things to understand is that bonds lose value as interest rates rise. And this is what happened to Silicon Valley Bank.

SVB loaded up on long-term government bonds when interest rates were much lower; the average weighted yield in their bond portfolio, in fact, was just 1.78%. But interest rates have been rising rapidly. The same bonds that SVB bought 2-3 years ago at 1.78% now yield between 3.5% and 5%, meaning that SVB was sitting on steep losses.”

According to the SVB’s 2022 annual report published January 19, 2023, they had $16 billion in capital and $15 billion in unrealized losses on their government bonds. So, they were ripe for a wipeout.

The problem is, if SVB, with its conservative loan-to-deposit ratio ended up insolvent due to government bonds tanking, then that likely means that everyone else is insolvent as well, including state and local governments, large corporations of all kinds, and the Federal Reserve. Anyone holding government bonds is sitting on huge losses as interest rates rise.

“Even the FDIC is suffering unrealized losses in its insurance fund, which is supposed to bail out banks that fail from their unrealized losses.” ~ Sovereign Research and Advisory Group

According to FDIC estimates, the unrealized losses of U.S. banks is approximately $650 billion and rising. Meanwhile, the FDIC’s deposit insurance fund (DIF), the fund that’s supposed to cover insured deposits (accounts up to $250,000), has a balance of just $128 billion.

See the problem? What’s worse, the DIF money doesn’t just sit there. It too is invested — in U.S. government bonds! As noted by the Sovereign Research and Advisory Group:

“So even the FDIC is suffering unrealized losses in its insurance fund, which is supposed to bail out banks that fail from their unrealized losses. You can’t make this stuff up, it’s ridiculous!”

And it’s only going to get worse if the Federal Reserve continues to increase interest rates. The problem is, interest rates need to be raised to curtail runaway inflation, but if they go up, more banks will sink due to their holdings in government bonds.

There’s just no way out.

Add to this insurmountable problem the fact that President Biden’s 2024 budget will raise the federal debt to $50.7 trillion by the end of 2033. It’s currently $31.459 trillion.

That’s a staggering amount of debt.

From a household perspective, you have no choice but to file for bankruptcy once your income cannot even cover the interest payment on your debt, and that’s basically where we are on a national level. As noted by The Balance:

“Most creditors don’t worry about a nation’s debt, also known as ‘sovereign debt,’ until it’s more than 77% of gross domestic product (GDP). That’s the point at which added debt cuts into annual economic growth, according to the World Bank. At the end of the second quarter of 2021, the U.S. debt-to-GDP ratio was 125%. That’s much higher than the tipping point …”

All of this is why it’s so important to prepare and become as independent as possible. The things we’ve taken for granted our entire lives may soon vanish, and what’s coming to replace them are not in your best interest unless you’re part of the globalist cabal that will exempt themselves from the slave system.

Becoming more resilient in the face of these changes could include moving cash into things that have a greater chance of withstanding inflation, such as precious metals (the actual metals, not the paper) and land, for example, and/or tradeable items. Shelf-stable foods may also be a wise investment, as could securing a private well or building a rain catchment system.

Also remember that artificial intelligence is the “beast” that drives the coming slave system. A formula created by the World Economic Forum’s philosophical guru, Yuval Noah Harari, describes the technocrats’ ever-growing ability to hack humans: B x C x D = AHH.

B stands for biological knowledge, C is computing power, D is data and AHH is the level of ability to hack a human being. AI needs massive amounts of up-to-the-minute data for the control system to work, so “starving the beast” also needs to be on your list.

That means eliminating apps and devices that collect your personal data, Google and Facebook being two of the biggest data miners. It also means rejecting CBDCs, as it’s not really a currency but a tool for population control, and digital identity, which will track everything you do, both online and in the real world, and will strip you of basic rights and freedoms based on your social credit score.

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Vitamin D Reduced Dementia Risk by 40%

  • A study in a cohort of 12,388 persons showed that vitamin D exposure over 10 years could lower the risk of dementia by 40%; women in the study experienced a greater benefit than men

  • There are 50 million people worldwide with dementia and experts estimate that number will nearly triple by 2050; vitamin D deficiency is also a widespread problem with a worldwide prevalence of up to 1 billion people

  • Vitamin D has a neuroprotective effect, can reduce the percentage of people who move from prediabetes to diabetes, and can help prevent and/or treat certain cancers, gastrointestinal diseases, uterine fibroids, lupus, obesity, and neurodegenerative diseases such as multiple sclerosis

  • There is a synergistic effect with magnesium, vitamin K2 and calcium and an imbalance may raise the risk of heart attack and stroke; the only way to determine how much sun exposure or supplementation you need is to test your vitamin D level

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In this 18-minute video, retired nurse educator John Campbell details the results of a 2023’ study

demonstrating the effect that vitamin D deficiency has on the development of Alzheimer’s disease and other forms of dementia. At this point, there is simply no question that optimizing vitamin D levels is a crucial part of maintaining optimal health.

Vitamin D is a fat-soluble vitamin, also referred to as calciferol. It can be found naturally in some foods and is produced endogenously when your skin is exposed to ultraviolet rays from the sun. Vitamin D supplementation in the U.S. is available as vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).

If you’re unsure of your vitamin D levels, it’s important to get tested. Seeking to optimize your vitamin D can potentially help you live longer since low levels have been associated with an increased risk of several health conditions,

some of which increase your risk of premature death.

The data demonstrating the efficacy of vitamin D in your health continue to mount and, as Campbell notes in his presentation, “This is cheap, it’s natural, it doesn’t cost anything and we’re not paying thousands of dollars per year to a pharmaceutical company.”

The researchers in the featured study

note that despite vitamin D deficiency having been associated with dementia in past studies, the role it plays remains unclear. The researchers gathered data from 12,388 persons from the National Alzheimer’s Coordinating Center who were dementia-free and had an average age of 71 at the time of enrollment.

The researchers measured baseline exposure to vitamin D and compared dementia-free survival between the groups of individuals who were exposed to vitamin D and those who were not. Vitamin D exposure was measured as taking vitamin D3, vitamin D2 or vitamin D3 plus calcium. The results showed that across all these groups, exposure to vitamin D was associated with a significantly longer time period without dementia and a lower incidence rate overall.

The researchers controlled for other covariates such as gender, cognitive status and apolipoprotein E (APOE) ε4. As Campbell explains,

the APOE gene is known to increase the risk of dementia in those who carry it. Approximately 25% of the population carries one APOE gene and 3% carries two. Individuals who have two genes will have a much higher risk than those who carry one.

The data suggest that all formulations of vitamin D tracked in the study reduced the incidence of dementia by 40% when compared to those who had no exposure. Interestingly, the effect was significantly greater in females versus males and in those with normal cognitive ability versus those who began the study with mild cognitive impairment (MCI).

The effect was also greater in those who were not APOE carriers versus those who were. The researchers concluded that “vitamin D has potential for dementia prevention, especially in the high-risk strata.”

Campbell notes that this was a large effect and while it does not prove correlation or causation, it suggests the results are more likely to be causal. The researchers plotted out the data published in figure A, which showed benefit to those exposed to vitamin D began roughly at the end of the first year and continued to confer greater benefit the longer the participants were followed.

Over the 10 years, Campbell notes that 2,696 of the participants got dementia. Of those, 2,017 (74.8%) had no exposure to vitamin D while only 679 (25.2%) who took vitamin D were diagnosed with dementia, which he calls an “impressive protective effect.”

Campbell asks why people with the APOE gene do not experience the same benefit from vitamin D as those who do not have the gene. He hypothesizes that they may require higher doses of vitamin D or the gene may override the benefits of the vitamin.

The researchers from the current study

note that 50 million people worldwide currently have dementia and the number is expected to nearly triple by 2050. Vitamin D deficiency is also recognized as a widespread problem, “with a worldwide prevalence of up to 1 billion.”

Past research has demonstrated that vitamin D has a neuroprotective effect. It is known to help clear amyloid beta aggregates in the brain,

which is a hallmark sign of Alzheimer’s disease. The researchers know that vitamin D has also demonstrated a neuroprotective effect against amyloid beta-induced tau hyperphosphorylation,

which is implicated in neurofibrillary tangles,

another structural abnormality found in Alzheimer’s disease.

Past studies have also implicated vitamin D deficiency in the increased risk of dementia. In a study published by the University of South Australia, researchers found those with the strongest association were in people with vitamin D levels below 10 ng/ml (25 nmol/L).

Low vitamin D levels were also associated with lower brain volumes, and genetic analyses suggested there’s a causal relationship between vitamin D deficiency and dementia.

Further, the researchers found that up to 17% of dementia cases in some populations may be prevented if people raised their vitamin D levels to 20 ng/ml (50 nmol/L).

In a separate study

of 1,658 people over a 5.6-year period, vitamin D deficiency was associated with a substantially increased risk of all-cause dementia and Alzheimer’s. When measuring Alzheimer’s disease specifically, severe vitamin D deficiency was linked to a 122% increased risk as compared to a 69% increased risk for those who were moderately deficient.

Campbell notes that past research has demonstrated that people taking vitamin D experience protection against progressing from prediabetes to diabetes. He notes that those who are more likely to get diabetes are also more likely to get dementia, so with the association of vitamin D and a lower risk of dementia, it “seems to make perfect sense to give these people extra vitamin D.”

Vitamin D also has a significant beneficial impact on cancer risk, possibly both preventing and treating the disease. In a 2020 reanalysis of a 2018 study

that measured the results of giving participants just 2,000 IUs a day, data showed a 17% reduced risk for metastatic cancer and death and as much as a 38% reduced risk in those who maintained a healthy weight.

This information is significant because initially this same study had concluded that vitamin D doesn’t reduce the overall risk of cancer at all, although it did “hint” that it might decrease the risk of cancer deaths. So. In the reanalysis, the team looked specifically at the risk of metastatic or fatal cancer.

When they did that, they found that “body mass may influence the relationship between vitamin D and a decreased risk of advanced cancer.” One of the corresponding authors, Dr. Paulette Chandler, commented:

“These findings suggest that vitamin D may reduce the risk of developing advanced cancers, Vitamin D is a supplement that’s readily available, cheap, and has been used and studied for decades. Our findings — especially the strong risk reduction seen in individuals with normal weight — provide new information about the relationship between vitamin D and advanced cancer.”

In still other studies, a 2020 review

published in the British Journal of Cancer noted that low vitamin D levels were associated with poor colorectal cancer survival and a 2019 review

of 10 randomized controlled trials found the reduction in mortality from cancer was “significant.”

As I have written in the past, research has also shown that higher levels of vitamin D can help prevent and/or treat gastrointestinal diseases,

inflammatory rheumatic diseases,



and neurodegenerative diseases such as multiple sclerosis.

And, as I found in my own peer-reviewed study,

vitamin D also reduces the risk for COVID-19 infection. Also, as I discuss in more detail below, vitamin D works even better when it’s balanced with other nutrients, such as magnesium and vitamin K2.

A 2022 study

also examined how Vitamin D may affect the development and progression of uterine fibroids. These are muscular tumors that grow in the wall of the uterus. They’re nearly always benign, but symptoms are difficult to live with. They occur in up to 70% of white women and more than 80% of black women, sometimes without symptoms.

The objective of the study was to find a treatment for fibroids that would preserve fertility. They enrolled 1,610 women and found that serum levels of vitamin D equal to or greater than 20 ng/mL (50 nmol/L) were associated with an estimated 9.7% reduction in the growth of fibroids when compared to people with vitamin D levels less than 20 ng/mL (50 nmol/L).

The researchers also found a 22% reduction in the incidence of fibroids and a 32% increase in fibroid tissue loss in individuals whose vitamin D levels were equal to or greater than 30 ng/mL (75 nmol/L) when compared to individuals whose levels were less.

If you are unable to maintain optimal levels of vitamin D from sensible sun exposure, it’s important to remember there are synergistic effects with other nutrients when you’re supplementing. When taking a vitamin D supplement, you may also need to increase your intake of magnesium, vitamin K2 MK7 and calcium.

Together, these vitamins work in tandem, and an imbalance is why calcium supplements have been associated with an increased risk of heart attack and stroke, and why some experience symptoms of vitamin D toxicity. Here’s a summary of some of the most important correlations:

  • Excessive vitamin D without adequate vitamin K2 may cause overabsorption of calcium, which in turn may result in calcium deposits in the tissue. Part of the explanation for these adverse side effects is that vitamin K2 keeps calcium in its appropriate place — in your teeth and bones and out of soft tissues and arteries.

    While the optimal ratios between vitamin D and vitamin K2 have yet to be established, taking somewhere between 100 and 200 micrograms (mcg) of K2 is beneficial. Telltale signs of vitamin K2 insufficiency include osteoporosis, heart disease and diabetes. You’re also more likely to be deficient if you rarely eat vitamin K2-rich foods.

  • Vascular calcification is also a side effect of low magnesium, so when taking vitamin D3, you need both vitamin K2 and magnesium to make sure everything is working properly.

  • Maintaining an appropriate calcium-to-magnesium ratio is also important, as magnesium helps keep calcium in your cells so they can function better. Based on your personal health needs an ideal ratio of calcium-to-magnesium may vary from 1-to-1 to an optimal 1-to-2.

  • Magnesium and vitamin K2 also complement each other, as magnesium helps lower blood pressure, which is an important component of heart disease.

I’ve long recommended a vitamin D level of 60 to 80 ng/ml (150-200 nmol/L) for optimal health and disease prevention. A level upward of 100 ng/mL also appears safe and beneficial for certain conditions, especially cancer.

Remember that the only way to determine how much sun exposure is enough and/or how much vitamin D3 you need to take is to measure your vitamin D level, ideally twice a year. The D*Action Project by GrassrootsHealth

is a cost-effective way to do this, while simultaneously progressing valuable research.

To participate, simply purchase a D*Action Measurement Kit and follow the registration instructions included. If you need to supplement, then GrassrootsHealth also has a vitamin D calculator

to help you estimate the dose you need to reach your target level.

You’ll input your weight, current vitamin D supplement, serum level and target level to find the maintenance dose needed to reach your desired level within three months. Once you’ve confirmed your vitamin D levels via testing, remember to retest in three to four months to make sure you’ve reached your target level.

If you have, then you know you’re taking the correct dosage and/or getting the right amount of sun exposure. If you’re still low (or have reached a level above 80 ng/ml), you’ll need to adjust your dosage accordingly and retest again in another three to four months.

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Disclaimer: The entire contents of this website are based upon the opinions of Dr. Mercola, unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked.

The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Mercola and his community. Dr. Mercola encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. The subscription fee being requested is for access to the articles and information posted on this site, and is not being paid for any individual medical advice.

If you are pregnant, nursing, taking medication, or have a medical condition, consult your health care professional before using products based on this content.