In response to coronavirus, Bill Gates, one of the world’s most sinister people, wants you to have certificates for vaccination or ‘recovered person’ to allow you to travel (and eventually have the info on a microchip ‘tattoo’).
New Yorkers need calm during coronavirus crisis, not the Empire State Building screaming death and despair
By Elias Marat,
As the world continues to battle the coronavirus, each of us owes a profound debt of gratitude to our medical and emergency frontliners, who have been performing feats of heroism with great costs to their own health and safety.
Nowhere is this truer than in New York City, which is currently the epicenter of the CoViD-19 pandemic in the United States. With over 36,000 cases and nearly 800 deaths as of Monday, hospitals and other critical services in the city have been pushed near the breaking-point as New Yorkers contend with the unprecedented health crisis.
On Monday evening, the iconic Empire State Building made a gesture of gratitude with a glaring light display filled with symbolism that would make clear the city’s gratitude toward critical healthcare personnel and first responders.
Instead, the gesture came across to many New Yorkers as ominous, unsettling, and just plain frightening.
In an announcement on Twitter, the building’s management wrote:
“Starting tonight through the COVID-19 battle, our signature white lights will be replaced by the heartbeat of America with a white and red siren in the mast for heroic emergency workers on the front line of the fight.”
Starting today, @empirestatebldg’s classic white lights will be replaced with America’s heartbeat and a siren of red and white in the mast as we pay respect to our heroic emergency workers on the front line of the fight. pic.twitter.com/XQB4UFr3GD
— Empire State Realty Trust, Inc (@ESRTsocial) March 30, 2020
And while the idea of solidarity and togetherness is always welcome in the resilient Big Apple, the sight of the skyscraper’s pulsating in blood-red amid low cloud cover struck many residents as simply bizarre—as if the city that never sleeps had become the realm of Mordor, fictional home to the Lord of the Rings arch-villain, Sauron.
Right, so, New York is Mordor and the Empire State Bldg is Barad-dûr. That’s the world we live in now. Ok. Totes ok. This is ok. Ok. https://t.co/d7WyE2uyLn
— Amaya Ramiel (@AmayaRamiel) March 31, 2020
“The @EmpireStateBldg reminding us that the city is in the middle of an emergency,” tweeted Rita King, who accompanied her tweet with video of the menacing scene.
While supportive of the cause, she added that she “recommend[s] that the siren be replaced by the iconic pulsing heartbeat effect to reassure our heroic healthcare workers that their efforts will succeed, and soothe nervous New Yorkers now sheltering in place.”
— Rita J. King (@RitaJKing) March 31, 2020
Raheem Kassam wrote:
Turning the Empire State Building into a massive flashing siren was either a stroke of artistic genius or a seriously intense way of panicking people.
— Raheem Kassam (@RaheemKassam) March 31, 2020
Another user added: “We know we’ve really screwed things up when the Empire State Building gets mad.”
Other residents hilariously lambasted the good-intentioned gesture that resulted in what appeared to be a “Glowing Red Tower of Portending Doom.’
Me: I think I’m finally learning how to keep my late-night coronavirus anxiety under control
The Empire State Building: https://t.co/DkZnp9dwwa
— Matt Ford (@fordm) March 31, 2020
love to have the glowing red beacon of doom on the skyline
— Extremely Socially Distant Tom Tomorrow (@tomtomorrow) March 31, 2020
having the Empire State Building glow bright red and start strobing in the fog is real nightmare shit and honestly I respect the hell out of it
— (@a_alesy) March 31, 2020
Cool very normal times with the Empire State Building turning into a blood red siren https://t.co/wyVG1gyPGl
— Laura Hudson (@laura_hudson) March 31, 2020
While New Yorkers greeted the poorly-executed gesture with characteristic good humor, the city has witnessed nothing less than a humanitarian disaster over the past days.
On Monday evening, the State of New York reported over 7,000 new cases of the virus, bringing the total to over 67,000, with more than half of the cases in NYC alone.
Governor Andrew Cuomo reiterated that the worst of the novel virus outbreak is still yet to come despite hundreds of people dying in the 24 hours prior.
As with all of Benjamin’s posts, feel free to “tune in” to that Higher Discernment while reading. In this article, I encourage all to remain free from any potential “fear engendering” ideas.
“The Battle for Planet Earth is reaching a climax as opposing forces try to use the “coronavirus pandemic” to achieve their agendas. The liberation forces are using the lockdown as an opportunity to arrest senior Khazarian Mafiosi, while the Satanists are hoping to vaccinate and microchip the general public back into submission, multiple sources agree. It’s almost as if reality is bifurcating, with one version filled with fear and death and other in breathless anticipation of planetary liberation.
“…many… will be or have been “coronavirused” (arrested), according to CIA and Pentagon white hats. One CIA source says: “They are putting out disinformation to keep this as classified as possible.” Merkel is going to have a third test and Macron also tests positive. This is code for they are being removed.”… “Abe is going to collapse the country’s economy because he works directly for the cabal so he has to be removed…”
“a purge has clearly accelerated inside the U.S. Pentagon sources say: “The Navy hospital ship USNS Mercy arrived at LA on March 27th and its sister USNS Comfort to NYC on March 30th but they may provide neither mercy nor comfort for arrested Zionists and pedos.
“…Bill Gates is calling for only people who have a vaccination certificate to be allowed to travel… NSA sources confirm this and say the cabal is hoping to get the sheeple to show up at the local Walmart to get vaccinated and micro-chipped in exchange for receiving “digital wallets.”
“The key battle to watch over the coming days will not be the one against the “pandemic” though, it will be the one over control of the financial system and thus the planet. On this front, any veteran market expert will tell you what is happening now is beyond a black swan event.
“…if you still do not think this pandemic is mostly hype take note of one thing: fewer people are dying now than before the so-called pandemic started…
“…what we are seeing for sure is a battle between fiat and reality backed money that will determine the future of this planet. The controllers of the old system with its G20, IMF, World Bank, and United Nations are pumping out trillions upon trillions of dollars in an attempt to keep their control grid intact. It is being advertised as well that the U.S. Treasury Department has taken over the Fed and will be handing out money to the common man… the increasingly desperate FED adding ever more zeroes to their promised numbers, their helicopter money is increasingly getting out of touch with reality.
“The FED is now obviously losing control of the petrodollar as the price of some grades of oil is falling to $4 per barrel. Experts are now predicting oil prices to go negative as the world runs out of places to store the stuff… So why isn’t the U.S. dollar collapsing? The answer to this is that the U.S. dollar is not controlled by the United States.
“…CIA version, conveyed face-to-face by a source, of what is going on with the pandemic: “Wuhan will not open; this is all a stage show for the media. There are still hundreds of apartment buildings sealed with the doors welded shut. China is starting with a new round of infections from returning nationals carrying a different strain of the bioengineered virus.”
“Interestingly the Satanic number 666 is again popping up in various news reports these days.
“Just watch and see how many bad guys vanish over the coming days and weeks. There is a lot we cannot say for operational reasons, but rest assured the good guys are winning. It’s revolution time.”
Abe, Macron, Merkel & Prince Charles to be “coronavirused,” as Battle for Planet Earth intensifies
By Benjamin Fulford March 30, 2020
The Battle for Planet Earth is reaching a climax as opposing forces try to use the “coronavirus pandemic” to achieve their agendas. The liberation forces are using the lockdown as an opportunity to arrest senior Khazarian Mafiosi, while the Satanists are hoping to vaccinate and microchip the general public back into submission, multiple sources agree. It’s almost as if reality is bifurcating, with one version filled with fear and death and other in breathless anticipation of planetary liberation.
First, let’s look at what the white hats are saying. Japanese Prime Minister Shinzo Abe, French President Emmanuel Macron, German Chancellor Angela Merkel, Prince Charles of the UK and many others will be or have been “coronavirused” (arrested), according to CIA and Pentagon white hats. One CIA source says:
“They are putting out disinformation to keep this as classified as possible.” Merkel is going to have a third test and Macron also tests positive. This is code for they are being removed.”
He adds, “Abe is going to collapse the country’s economy because he works directly for the cabal so he has to be removed. (Since this is the age of deep fake computer graphics, here in Japan I will keep in touch with press ID carrying colleagues to see if the real Abe vanishes).” Pentagon sources agree and say, “regime change may also happen in Japan as Shinzo was forced to delay the Tokyo Olympics for one year.”
Maybe it’s the fear of American assassins coming for Abe that has prompted Japan to consider an entry ban on all American citizens.
In any case, a purge has clearly accelerated inside the U.S. Pentagon sources say:
“The Navy hospital ship USNS Mercy arrived at LA on March 27th and its sister USNS Comfort to NYC on March 30th but they may provide neither mercy nor comfort for arrested Zionists and pedos. Also, truckers have been ordered to not deliver to New York as [U.S. President Donald] Trump personally went to Norfolk, Virginia to send off USNS Comfort to New York City.”
Now let us look at what the dark side is up to. In the video at the link below, starting around the 15:20 mark, Bill Gates is calling for only people who have a vaccination certificate to be allowed to travel.
NSA sources confirm this and say the cabal is hoping to get the sheeple to show up at the local Walmart to get vaccinated and micro-chipped in exchange for receiving “digital wallets.” This is serious folks, do not let them scare you into being vaccinated because I guarantee you any vaccine they provide will be worse than whatever it is they say they are going to protect you from. U.S. presidential candidate Joe Biden was probably telling the truth when he said, “We have to take care of the cure, that will make the problem worse no matter what.”
The key battle to watch over the coming days will not be the one against the “pandemic” though, it will be the one over control of the financial system and thus the planet. On this front, any veteran market expert will tell you what is happening now is beyond a black swan event. The United States military did not call up one million reservists and move its headquarters to an underground bunker because of a mostly bogus coronavirus threat. https://www.whitehouse.gov/presidential-actions/eo-order-selected-reserve-certain-members-individual-ready-reserve-armed-forces-active-duty/
By the way, if you still do not think this pandemic is mostly hype take note of one thing: fewer people are dying now than before the so-called pandemic started.
Anyway, to understand why the planet is now moving into historically uncharted territory take a look at this NASA…
…video of activity around the sun. I do not usually write about space stuff but this was sent to me by several trusted sources. It appears to show the solar system undergoing some sort of fundamental shift.
Now take a look at this photograph of FRB chief Jerome Powell
Maybe it is just my imagination but if you look at his eyes, he doesn’t appear to be human. Is he a Reptilian overlord of the sort David Icke describes?
OK, enough space stuff for now. Regardless of whether cosmic forces are involved or not, what we are seeing for sure is a battle between fiat and reality backed money that will determine the future of this planet.
The controllers of the old system with its G20, IMF, World Bank, and United Nations are pumping out trillions upon trillions of dollars in an attempt to keep their control grid intact. It is being advertised as well that the U.S. Treasury Department has taken over the Fed and will be handing out money to the common man. However, as Catherine Austin Fitts notes, (https://en.wikipedia.org/wiki/Catherine_Austin_Fitts a former high-level establishment insider), control of the trillions of dollars being pumped out by the FED has been given to arch-cabal company Blackrock. “The guy who runs Blackrock was going to be Clinton’s Secretary of the Treasury. I used to work with Blackrock. NO PATRIOTS THERE!,” she tweets.
Despite the increasingly desperate FED adding ever more zeroes to their promised numbers, their helicopter money is increasingly getting out of touch with reality. Creating dollars out of thin air means nothing to real-world restaurants, airlines and oil companies, etc. watching their businesses collapse.
One sign of the fiat collapse is the fact that physical gold and silver are now far more expensive than their paper equivalents.
What is interesting though is that the Perth Mint in Australia, still has physical gold and silver for sale.
The Perth mint is the only mint acknowledged by the Western financial system that is smelting Asian off ledger gold. This is especially interesting since three Chinese warships just sailed into Sydney harbor, apparently without the knowledge of the Australian military. Has China just seized control of Australia?
The Russians have also made a huge move by de facto seizing the world’s largest oil reserves in Venezuela. The Russian government now owns them. This means any move by the Washington DC regime to seize Venezuelan oil will lead to war with nuclear-armed Russia. https://tass.com/economy/1136999
The FED is now obviously losing control of the petrodollar as the price of some grades of oil is falling to $4 per barrel. Experts are now predicting oil prices to go negative as the world runs out of places to store the stuff.
So why isn’t the U.S. dollar collapsing? The answer to this is that the U.S. dollar is not controlled by the United States. There are many countries producing U.S. dollars including China, Japan, and Indonesia. What is happening is that the formerly oil-backed dollars produced by the faction controlling Washington DC are not being accepted by most other countries. Japanese or Chinese made U.S. dollars, though, are in high demand. Seizing Australia and the Perth mint was necessary to ensure the cabal couldn’t get its hands on more gold to back its dollars with, Asian secret society sources say.
Now, for a look at what the cabal has planned for China in this undeclared World War III, let us look at a CIA version, conveyed face-to-face by a source, of what is going on with the pandemic:
“Wuhan will not open; this is all a stage show for the media. There are still hundreds of apartment buildings sealed with the doors welded shut. China is starting with a new round of infections from returning nationals carrying a different strain of the bioengineered virus. Before the end of the year, China is scheduled to implode with hundreds of millions of deaths. The cabal’s goal is to eliminate up to half of its population.
There are five different strains of this weaponized coronavirus created at Ft. Detrick. The strains that hit China and Japan are different from each other but Italy and Iran have the same strain.
India will only have minor problems and the death toll there will be marginal. The lockdown will be enforced by the cabal, which still controls India. The pandemic should be winding down by July, so by summer, it will all be taken care of.”
It is interesting to note Israeli Defense Minister Naftali Bennett said on Israeli TV that the pandemic “might take two months, it might take three months, it might take a bit longer but that is the plan.” Then we have a Rabbi telling the Jews not to worry because the coronavirus is “only for the goyim.”
Furthermore, we have CIA sources in South East Asia noting that because “100 people in a country of 270 million died from the ‘new flu’ they are shutting down the country.” He adds, “This is the largest scam ever pulled on humanity. People are waking up all over the world as to what this really is.”
“We see the whole affair as a pre-emptive strike that has gone spectacularly wrong. Now we will see a counteroffensive designed to level to the ground all concerned,” is what MI6 had to say about the pandemic talk.
Interestingly the Satanic number 666 is again popping up in various news reports these days. Two examples are linked below.
These BBC and Fox News stories are hinting that asteroids will be used next to scare people after the pandemic show fizzles to an end.
We are also hearing from many sources that preparations for what is happening now have been going on for quite some time. Take a look at this phrase from a September 2007 conference called, Defense in 2020 and Beyond:
“The British Armed Forces Joint Doctrine and Concepts Center expects a general collapse of the global order in the next decade, and other strategic thinkers are equally pessimistic.”
The “strategic thinkers” may have known their fiat-based control grid was mathematically doomed to lose touch with reality. However, they apparently failed to see the collapse of the old control grid paving the way for a phoenix-like rise of a new age. Soon our concrete and steel cities will become green with vegetation and filled with abundant animal life.
Remember the cabal requires fear and hate in order to stay in control. Friendship and love, when backed by overwhelming military force, will prevail. Just watch and see how many bad guys vanish over the coming days and weeks. There is a lot we cannot say for operational reasons, but rest assured the good guys are winning. It’s revolution time.
Although officials are not using this exact term, we are now in a War on Bioterror as government after government has declared war on the new coronavirus strain COVID-19.
While melatonin works as a natural sleep regulator, it affects health in many other important ways as well.1 For example, melatonin:
Is a potent antioxidant2
Plays an important role in cancer prevention3
Is important for brain, cardiovascular and gastrointestinal health4
Boosts immune function in a variety of ways
May improve the treatment of certain bacterial diseases, including tuberculosis5
Helps quell inflammation
May prevent or improve autoimmune diseases, including Type 1 diabetes6
Is an important energy hormone7 — If your sleep efficiency is impaired, meaning you’re not sleeping as deeply as you should, for as long as is ideal, then your energy level is going to be adversely affected
As noted in the Journal of Critical Care:8
“Melatonin is a versatile molecule, synthesized not only in the pineal gland, but also in many other organs. Melatonin plays an important physiologic role in sleep and circadian rhythm regulation, immunoregulation, antioxidant and mitochondrial-protective functions, reproductive control, and regulation of mood. Melatonin has also been reported as effective in combating various bacterial and viral infections.”
Melatonin — A Potential Treatment for Sepsis?
The Journal of Critical Care paper,9 published in 2010, further highlights the potential role of melatonin in the treatment of sepsis (blood poisoning), a life-threatening condition triggered by a systemic infection that causes your body to overreact and launch an excessive and highly damaging immune response.
Unless promptly diagnosed and treated, it can rapidly progress to multiple-organ failure and death. The cytokine storm response appears to be a primary way by which the novel coronavirus COVID-19 (also referred to as SARS-CoV-2, due to its similarity to the SARS coronavirus) claims the lives of those who are immunocompromised and/or elderly. According to the Journal of Critical Care:10
“Melatonin is an effective anti-inflammatory agent in various animal models of inflammation and sepsis, and its anti-inflammatory action has been attributed to inhibition of nitric oxide synthase with consequent reduction of peroxynitrite formation, to the stimulation of various antioxidant enzymes thus contributing to enhance the antioxidant defense, and to protective effects on mitochondrial function and in preventing apoptosis.
In a number of animal models of septic shock, as well as in patients with septic disease, melatonin reportedly exerts beneficial effects to arrest cellular damage and multiorgan failure.”
In summary, melatonin appears to reverse septic shock symptoms by:11
- Decreasing synthesis of proinflammatory cytokines
- Preventing lipopolysaccharide (LPS)-induced oxidative damage, endotoxemia and metabolic alterations
- Suppressing gene expression of the bad form of nitric oxide, inducible nitric oxide synthase (iNOS)
- Preventing apoptosis (cell death)
According to the authors, the ways in which melatonin prevents septic shock are complex:
“Apart from action on the local sites of inflammation, melatonin also exerts its beneficial actions through a multifactorial pathway including its effects as immunomodulatory, antioxidant and antiapoptotic agent.”
Glyphosate, Melatonin and COVID-19
Stephanie Seneff, Ph.D., senior research scientist at MIT, also recently brought the potential role of melatonin to my attention, specifically in regard to the current coronavirus (COVID-19) outbreak. In an email to me, Seneff explains:
“I just figured something out about COVID-19 and glyphosate. Upper respiratory infections are a high risk for people who have a deficiency in mannose binding lectin (MBL). MBL has a long sequence in the protein that looks like collagen (GxyGxyGxy…): GINGFPGKD GRDGTKGEKG EPGQGLRGLQ GPPGKLGPPG NPGPSGSPGP KGQKGDPGKS.
I just discovered that there are two lung surfactant proteins (A and B) which also have this GxyGxy pattern in their stalks. Here’s the relevant sequence in lung surfactant protein A: GSP GIPGTPGSHG LPGRDGRDGL KGDPGPPGPM GPPGEMPCPP GNDGLPGAPG IPGECGEKGE PGERGPPGLP. Here’s what UniProt says about this protein:12
‘In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration … Can recognize, bind, and opsonize pathogens to enhance their elimination by alveolar macrophages.’
I would wager that glyphosate disrupts the collagen-like stalk of the lung surfactants preventing them from binding to and clearing the COVID-19 virus … I was wondering why the elderly are suffering much more from sepsis and cytokine storm during COVID-19 infections. A significant difference in older patients compared to younger patients is their melatonin levels. Another good insight and treatment approach?”
Melatonin Ameliorates Cytokine Responses
In her email, Seneff goes on to cite a 2014 study13 in the Journal of Pineal Research which, like the Journal of Critical Care paper, points out that melatonin accumulates in mitochondria and has both antioxidant and anti-inflammatory activity that could be useful in the treatment of sepsis.
Melatonin is derived from serotonin, which in turn is derived from tryptophan, one of the three aromatic amino acids that are products of the shikimate pathway. Glyphosate famously disrupts the shikimate pathway in weeds, and this is believed to be the main mechanism by which it kills the weeds. Our gut bacteria also produce tryptophan via the shikimate pathway, so glyphosate can be expected to reduce the bioavailability of tryptophan as a precursor to melatonin.
The study mentioned above was a Phase 1 dose escalation study in healthy volunteers to evaluate the tolerability and health effects of melatonin at various dosages. They also assessed the effect of melatonin in an ex vivo whole blood model mimicking sepsis.
No adverse effects were reported for dosages ranging from 20 milligram (mg) to 100 mg, and the blood model testing revealed melatonin and its metabolite 6-hydroxymelatonin “had beneficial effects on sepsis-induced mitochondrial dysfunction, oxidative stress and cytokine responses …” The authors further explain:14
“Oxidative stress in patients with sepsis has been consistently described over the last 20 years. Mitochondrial dysfunction initiated by oxidative stress drives inflammation and is generally accepted as playing a major role in sepsis-induced organ failure.
It has been recognized that exogenous antioxidants may be useful in sepsis, and more recently, the potential for antioxidants acting specifically in mitochondria has been highlighted.
We showed previously that antioxidants targeted to mitochondria, including melatonin, reduced organ damage in a rat model of sepsis. Exogenous melatonin has potent antioxidant activity, and it accumulates throughout cells, particularly in mitochondria. Metabolites of melatonin also have antioxidant activity, and products from the reactions with oxidant species are also antioxidants.
In vitro models of sepsis show that melatonin and its major hydroxylated metabolite, 6-hydroxymelatonin, are both effective at reducing the levels of key inflammatory cytokines, oxidative stress, and mitochondrial dysfunction. In rat models of sepsis, melatonin reduces oxidative damage and organ dysfunction and also decreases mortality.
The dose needed for antioxidant action is thought to be considerably higher than that given for modulation of the sleep–wake cycle, but the actual dose required in man is unclear, particularly because the major bioactive effects of oral melatonin in the context of inflammation are likely to be mediated primarily by metabolite levels.”
Antiseptic Effects of Melatonin
More recently, a 2019 animal study15 in the journal Frontiers in Immunology discusses how melatonin can protect against polymicrobial sepsis — i.e., sepsis caused by more than one microbial organism — a hallmark of which is severe loss of lymphocytes through apoptosis, resulting in a twofold higher lethality than unimicrobial sepsis (sepsis caused by a single microbe).16
In this case, melatonin appears to offer protection by having an antibacterial effect on white blood cells called neutrophils. A high neutrophil count is an indicator for infection. According to the authors of the 2019 study:
“Melatonin treatment inhibited peripheral tissue inflammation and tissue damage … consequently reducing the mortality of the mice. We found that macrophages and neutrophils expressed melatonin receptors.
Upon depletion of neutrophils, melatonin-induced protection against polymicrobial infection failed in the mice, but melatonin treatment in macrophage-depleted mice attenuated the mice mortality resulting from polymicrobial sepsis.
Moreover, melatonin treatment promoted the development of the neutrophil extracellular trap (NET), which contributed to anti-bacterial activity during polymicrobial infection, whereas the phagocytic activities of neutrophils were inhibited by melatonin.
The data from this study support previously unexplained antiseptic effects of melatonin during a polymicrobial infection and could be potentially useful for human patients with sepsis.”
Understanding COVID-19 Infection
The potential role of melatonin in COVID-19 infection was also addressed in an extensive and fully referenced March 14, 2020, article by medical researcher Doris Loh, published in the Italian online magazine Evolutamente.17
“Unofficial reports from doctors and healthcare workers from COVID-19 frontlines in Italy described most patients displayed symptoms of bilateral interstitial pneumonia that required intubation (invasive ventilation) to assist difficulty in breathing.
Even young patients without comorbidities have been observed with severe pneumonia that required intensive care in ICUs,” Loh reports. “Why does SARS-CoV-2, the coronavirus responsible for COVID-19 infection, induce pneumonia in adult patients regardless of age?”
One answer may be because the viral load in those with COVID-19 infection is extremely high — 1,000 times higher than the viral load seen in SARS patients back in 2003.18
Preliminary research19 cited by Loh shows the COVID-19 virus is actively replicating in the throat during the first five days after the onset of symptoms. This higher viral load could be what allows the virus to overwhelm even the immune system of some younger and healthier individuals.
Inflammasomes and Cytokine Storms
Another mechanism that can help explain the high virulence of COVID-19 compared to SARS has to do with a furin cleavage site in the spike protein of the virus that wasn’t present in the SARS virus. As explained by Loh, “The presence of furins on almost all cell surfaces allow a dramatically increased ability to fuse to host cells, facilitating viral entry …” She adds:20
“Cleavage specificity can dictate the tropism and virulence of the virus. The fact that COVID-19 has cleavage sites for furin enzymes renders this virus to be highly pathogenic, with the capacity to replicate in MULTIPLE tissues and organs due to how furins are utilized and distributed in the human body.
Furin-like cleavage in human coronaviruses have been associated with the development of neurological diseases where the invasiveness and efficient establishment of lower pathogenicity can result in persistent infection of the central nervous system.
Thus it was not a surprise when in early March of 2020, doctors from Beijing Ditan Hospital affiliated to Capital Medical University, a designated institution for COVID-19 treatment, showed for the first time that COVID-19 can attack the human central nervous system, causing symptoms of encephalitis.
The presence of furin enzymes on all cell surfaces cleaves and activates the SARS-CoV-2 in a wide range of tissues and organs. Activated SARS-CoV-2 then unleashes NLRP3 inflammasomes, initiating a flurry of immune reactions that can result in deadly cytokine storms.”
As the name implies, inflammasomes are part of your natural immune response that senses the presence of pathogens and other factors that could pose a threat. When a pathogen is detected, inflammasomes are activated and start releasing proinflammatory cytokines.
The inflammasome NLRP3, specifically, has been identified as a key culprit in acute respiratory distress syndrome (ARDS) and acute lung injury, both of which are potential outcomes of COVID-19 infection.21
The cytokine storm associated with COVID-19 infection appears to be due to the virus’ ability to stimulate your immune response via viroporins, virally-encoded ion channel proteins that in turn trigger the activation of NLRP3 inflammasomes. As explained by Loh, the more functional a virus’ viroporins are, the greater its viral replication rate and subsequent pathogenesis.
Is Elevated Melatonin Sparing Young Children from COVID-19?
As noted by Loh, the fatality rate of COVID-19 increases linearly with age, with patients over the age of 80 having the highest death rate.22,23,24 As of yet, the explanation for why children are less likely to contract the infection or show symptoms even when they are infected,25 is unknown.
Loh, however, raises the possibility that it might have something to do with melatonin production. She cites research showing melatonin production peaks in early childhood, steadily dropping once puberty hits. By the time you’re in your late 50s, melatonin production drops to negligible levels.
“What does melatonin have to do with SARS-CoV-2?” Loh asks. The answer is that melatonin helps inhibit NLRP3 inflammasomes.
“The fact that the pro-inflammatory cytokine storm effects are induced by the activation of NLRP3 inflammasomes, the ability of melatonin to INHIBIT NLRP3 inflammasome elevates this powerful molecule to a truly unique position in the fight against COVID-19,” Loh writes.26
“This also means that if a patient, regardless of age, has adequate melatonin, the infectiousness of COVID-19 will be greatly reduced, and the chances of developing ARDS/ALI significantly diminished.”
In her article, Loh references a number of scientific articles to support her claims. Aside from studies showing melatonin inhibits damage associated with sepsis, studies have also shown it can counteract severe inflammation and “markedly reduce pulmonary injury [and] lower infiltration of macrophages and neutrophils into lungs … by inhibiting the activation of NLRP3 inflammasomes,” thus protecting against acute lung injury.
Melatonin levels are also doubled in the third trimester of pregnancy compared to the first trimester,27,28 which may help explain why pregnant women infected with COVID-19 and their babies have gotten by fairly unscathed. A 2020 rodent study29 even demonstrated that melatonin can help protect against lung injury caused by mechanical ventilation intervention.
“The full therapeutic potential of melatonin in its ability to modulate the immune system, especially the critical function of suppressing cytokine storms to prevent progression of acute respiratory distress syndrome (ARDS) and respiratory failure in infected patients was clearly demonstrated in a study by Huang et al. (2019).
Huang et al. infected rodents with the highly lethal and infectious H1N1 influenza A virus. Co-treatment of these infected rodents with melatonin and an antiviral drug significantly increased their survival rates compared to mice treated only with antivirals alone,” Loh writes.
The role of NLRP3 inflammasomes in COVID-19 infection also adds support for the use of ascorbic acid (vitamin C), as ascorbic acid has been shown to inhibit NLRP3 Inflammasomes in a dose-dependent fashion by scavenging reactive oxygen species in the mitochondria.30,31
“Thus, the combined use of melatonin and ascorbic acid may prove to be most effective in the treatment for COVID-19 patients, especially those with cardiovascular and hypertension comorbidities,” Loh suggests.32
You can learn more about the use of intravenous vitamin C against sepsis and coronavirus infection in “Essential Nutrition to Protect Yourself From Coronavirus.”
Avoid ACE Inhibitors During COVID-19 Outbreak
Nutrients and drugs that might be best avoided during this outbreak are those that inhibit angiotensin-converting enzyme (ACE). What’s the problem with ACE inhibitors? As explained by Loh, ACE inhibitors increase expression of ACE2, and COVID-19 infects host cells by binding to ACE2 receptors found on epithelial cells in your lungs, intestines, kidneys and blood vessels.33
ACE inhibitors, i.e., medications that relax and dilate your blood vessels, are commonly prescribed for high blood pressure, certain types of heart failure, stroke prevention and for the prevention and treatment of kidney disease. These drugs work by inhibiting the specific isoform of ACE, ACE1. As a consequence, ACE2 is upregulated. This is problematic with regard to COVID-19, because the virus gains entry to infect cells specifically via the ACE2 protein acting as a receptor.
Loh cites research34 published in The Lancet Respiratory Medicine suggesting that taking an ACE inhibitor, be it a medication or a nutritional supplement, may worsen your risk of COVID-19 infection and your risk of complications.
“Melatonin, nitric oxide and ascorbic acid (vitamin C) are all inextricably intertwined and deeply involved with ACE2,” Loh writes.35
“Melatonin, nitric oxide and ascorbic acid can reduce COVID-19 virulence by inhibiting NLRP3 inflammasomes to stop the perpetuation of cytokine storms. Their critical roles in biochemical reactions and biological pathways that involve ACE2 must be fully explored as part of our fight against COVID-19.”
At the end of her article, Loh offers suggestions for melatonin and vitamin C dosages, along with contraindications and timing of supplementation.
Stay Calm and Take Commonsense Precautions
Keep in mind that while all of this information may sound concerning, the lethality of COVID-19 is quite low for those under the age of 65. According to a March 18, 2020, report by the U.S. Centers for Disease Control and Prevention, preliminary mortality rates for COVID-19 in the U.S. are:36
- Zero% for adolescents under the age of 19
- Less than 1% among those aged 20 to 54
- 1% to 3% among 55- to 64-year-olds
- 11% for those aged 65 to 84
- 10% to 27% among those over the age of 85
To minimize the spread of infection, remember to:37
- Frequently wash your hands with soap and water for at least 20 seconds. For further details, see “The Impact of Effective Handwashing Against Infection”
- Avoid touching your eyes, nose and mouth
- If you need to cough, cough into your flexed elbow or disposable tissue. Discard the tissue in a trash can and wash your hands
- If feeling unwell, stay home and avoid public spaces
If you have symptoms of illness such as coughing or sneezing, be sure to wear a surgical mask to contain the spread whenever you’re around others. For additional details about the use of surgical or N95 respiratory masks, see “Will Wearing a Mask Protect You Against Coronavirus?”
The scent of fresh-cut grass, your mom’s chicken soup or burning leaves may instantly transport you to a distant memory, one you can suddenly recall with razor-sharp clarity.
So-called odor-evoked memories often come along with powerful emotions and are known to activate the “neurolobiological substrates of emotional processing,” according to neuroscientist Rachel S. Herz, an adjunct assistant professor of psychiatry and human behavior at Brown University.1
Research published in Learning and Memory2 added to this, suggesting that odors may modulate the dynamics of memory consolidation, including memories linked to fear, and could potentially be used therapeutically to help people recall memories or treat memory-related mood disorders, such as post-traumatic stress disorder (PTSD).3
“If odor could be used to elicit the rich recollection of a memory — even of a traumatic experience — we could take advantage of that [therapeutically],” study author Steve Ramirez, assistant professor of psychology and brain sciences at Boston University, said in a news release.4
The Systems Consolidation Theory of Memory
The prevailing theory of memory formation — the systems consolidation theory — suggests that memories are initially processed in the brain’s hippocampus, giving the memory rich details. Over time, however, as memories become older or more remote, they become less dependent on the hippocampus and more dependent on processing by the front of the brain — the prefrontal cortex.
During this transition, which occurs particularly during sleep, memories may lose many of their rich contextual details. Further, memories that are retrieved shortly after an experience involve reactivation of cells in the hippocampus whereas retrieval of a memory later is thought to involve reactivation of cells in the prefrontal cortex.5
The systems consolidation theory explains why memories tend to become less detailed or clear as time goes by, as well as why people with a damaged hippocampus have trouble forming new memories while those with prefrontal cortex damage may have trouble remembering memories from the past.6
The theory, however, is just that — a theory — and it has some challenges as well. Researchers noted in Learning and Memory, “[P]eople often retrieve remote memories that are vivid and highly detailed. Likewise, several studies have shown that there is activity in both structures during both recent and remote memory recall … and that damage to the HPC [hippocampus] sometimes affects remote memory as well as recent memory.”7
Particularly in PTSD, people may recall intense memories years after the trauma occurred, which seemingly contradicts the systems consolidation theory, leading the researchers to conduct a study to clarify some of these contradictions.
Scent Alters the Way Memories Are Processed
In a study on mice, researchers from Boston University’s Center for Systems Neuroscience startled mice with electric shocks while in a special container to induce fear memories. Half the mice were exposed to almond extract scent during the shocks while the other half received no scent exposure.
The next day, the same experiment took place, but without any electric shocks given. The odor group was exposed to the scent of almond extract while in the special container while the other group had no scent exposure. The idea was to prompt the mice to recall the fearful memory of being shocked — something all the animals did, as evidenced by significant activation of the hippocampus.
The memory recall session was repeated again 20 days later. In the no-odor group, the prefrontal cortex was activated, suggesting it was responsible for processing the fear memory, as researchers had expected. In the odor group, however, significant activity was still observed in the hippocampus. Ramirez noted:8
“[This finding suggests] that we can bias the hippocampus to come back online at a timepoint when we wouldn’t expect it to be online anymore because the memory is too old. Odor can act as a cue to reinvigorate or reenergize that memory with detail.”
It’s possible that odors may delay a memory being processed in the prefrontal cortex, or that an odor reactivates the hippocampus to restore details of a memory that’s already shifted to the prefrontal cortex.
While the specifics aren’t yet known, it’s possible that odors could be harnessed to help people with PTSD actively recall traumatic memories, so that they could then be suppressed or dampened using behavioral interventions.
“Now that we know that odor can shift memories to become more hippocampus dependent, we could potentially develop strategies that engage or disengage the hippocampus,” Ramirez said, adding, “We can potentially view memory as its own kind of drug — as an antidepressant or [anxiety reducer]. And [odor] could be an experimentally controllable factor that we could deliver to people. It may be a very powerful tool.”9
Memories Induced by Scent Are More Emotional
Odor-evoked memory is dubbed the “Proust phenomenon” after a literary anecdote where Marcel Proust took a bite of a biscuit dipped in Linden tea and was transported to a moment in his childhood that he had long forgotten. Odor-evoked memories, Herz explained, are unique from memories evoked by other stimuli, such as verbal or visual stimuli.
Not only are they more rare and less frequently thought about, but they tend to come from early in life, typically within the first decade. What’s more, autobiographical memories triggered by odors tend to be much more emotional and have the perception of bringing people back to the original time and place that their memories occurred.
Part of the unique intensity of odor-evoked memories has to do with the way scent is processed by your brain. Smells get routed through your olfactory bulb, which the smell-analyzing region in your brain. It’s closely connected to your amygdala and hippocampus, brain regions that handle memory and emotion. According to Herz:10
“Odor-evoked memories are exceptionally viscerally involving because the neuroanatomy of olfaction has a privileged and unique connection to the neural substrates of emotion and associative learning.
The primary olfactory cortex includes the amygdala, which processes emotional experience and emotional memory, as well as the hippocampus, which is involved in associative learning. Thus, the mere act of smelling activates the amydala-hippocampal complex.”
Odor-Evoked Memories Influence Psychological, Physical Health
By boosting mood, lowering stress and reducing inflammation, it’s likely that the powerful emotions elicited by positive odor-evoked memories can influence psychological and physiological health.
“Any odor that for a given individual evokes a happy autobiographical memory has the potential to increase positive emotions, decrease negative moods, disrupt cravings, lower stress and decrease inflammatory immune responses, and thereby have a generally beneficial effect on psychological and physiological well-being,” Herz wrote,11 noting that individuals may also experience unique effects like improvements in self-confidence, motivation and vigor depending on the emotions a specific memory invokes.
For example, if an odor triggers a memory of winning a sporting event, it could energize your behavior and trigger beneficial physiological effects, making it a reliable therapeutic agent. Likewise, odors that evoke pleasant memories could be used as reminders of safe or happy places and events, making them useful for the treatment of psychiatric conditions and reducing stress and anxiety.12
The unique anatomy of the olfactory pathways hints at the importance of odors in emotions, learning, memory and more. While other sensory systems pass through the thalamus to reach the cortex, odors get relayed directly to the limbic system in the brain, which is associated with memory and emotional processes.
This is why odors have such a powerful influence on mood, information acquisition and even social interactions. As noted in Frontiers in Behavioral Neurosciences, memory is but one crucial behavior influenced by odors:13
“Indeed, olfaction is crucially involved in behaviors essential for survival of the individual and species, including identification of predators, recognition of individuals for procreation or social hierarchy, location of food, as well as attachment between mating pairs and infant-caretaker dyads.”
Aromatherapy: Another Way Scents Influence Mood and More
Aromatherapy — the use of plant-based aromas to influence mood and wellness — is not the same as odor-evoked memory. In the case of the psychological and physiological effects induced by odor-evoked memories, the odor has such effects because of the memories and emotions attached to it as a result of past personal experience.14
This isn’t to say that aromatherapy isn’t also beneficial for health and wellness, just that it works in a different, more generalized way. Many ancient cultures, including the Chinese, Indians, Egyptians, Greeks and Romans used essential oils in cosmetics, perfumes and drugs for purposes ranging from spiritual to therapeutic.15
In the modern day, aromatherapy is used in health care settings, health spas and homes, both by professional aromatherapists and amateurs, while accumulating research backs up its many potential uses and benefits.
For instance, the two primary terpenoid constituents of lavender essential oil, linalool and linalyl acetate, have anxiety-reducing effects, and lavender essential oil is known to induce a calming effect without side effects such as sedation.16
Lavender also has an effect on the nervous system, and when inhaled it’s believed to act via the limbic system, particularly the amygdala and hippocampus,17 although it may have effects even beyond mood and anxiety.
In a study on patients undergoing open heart surgery, a cotton swab containing lavender essential oil was placed in the patients’ oxygen mask for 10 minutes. The aromatherapy led to significant reductions in blood pressure and heart rate, with researchers concluding it could be “used as an independent nursing intervention in stabilizing mentioned vital signs.”18
Beyond lavender, a study on rats showed that inhaling Roman chamomile essential oil for two weeks reduced depressive-like behaviors,19 while essential oils placed nightly on towels around dementia patients’ pillows resulted in significantly longer total sleep time, increased sustained sleep and reduced early morning awakening.20
While it’s best to consult an experienced aromatherapist before delving into essential oils, generally speaking if you’re looking to feel energized and uplifted, consider essential oils such as peppermint, grapefruit, lemon, neroli and wild orange while more calming oils include lavender, chamomile, bergamot, ylang ylang and vetiver. For more information, consult our Ultimate Guide to Herbal Oils.
Loss of Sense of Smell Also Gives Clues About Health
Paying attention to any changes in your sense of smell, including a loss of it, is also important. In a study of 3,005 community-dwelling adults, those who had a dysfunctional sense of smell were more likely to die in the next five years than those with a good sense of smell.
In fact, olfactory function was deemed to be one of the strongest predictors of five-year mortality and researchers suggested it may “serve as a bellwether for slowed cellular regeneration or as a marker of cumulative toxic environmental exposures.”21
An inability to identify odors is also an early symptom of neurological disorders, including Alzheimer’s disease and Parkinson’s disease.22 So, make a conscious effort to keep track of your sense of smell, using it for memory recall, mood boosts and as a gauge for your health should it dissipate.
While odor-evoked memories can be powerful tools for health and behavior as well, they depend largely on happenstance, in that a scent must be introduced at the precise moment that a memorable event is occurring — then that scent must later be introduced to evoke the memory.
It happens often enough that virtually everyone reading this has experienced it, but if you’re looking for a more direct way to harness the power of odors over your health, aromatherapy can be very useful.
By Anna Von Reitz
By Anna Von Reitz
By Anna Von Reitz
2) Do Not Blaspheme God
3) Do Not Murder
4) Do Not Engage in Incestuous, Adulterous or Homosexual Relationships
5) Do Not Steal
6) Do Not Eat of a Live Animal
7) Establish Courts/Legal System to Ensure Law Obedience