Former Chief Science Officer for Pfizer Says “Second Wave” Faked on False-Positive COVID Tests, “Pandemic is Over”

By Ralph Lopez,

In a stunning development, a former Chief Science Officer for the pharmaceutical giant Pfizer says “there is no science to suggest a second wave should happen.” The “Big Pharma” insider asserts that false positive results from inherently unreliable COVID tests are being used to manufacture a “second wave” based on “new cases.”

Dr. Mike Yeadon, a former Vice President and Chief Science Officer for Pfizer for 16 years, says that half or even “almost all” of tests for COVID are false positives. Dr. Yeadon also argues that the threshold for herd immunity may be much lower than previously thought, and may have been reached in many countries already.

In an interview last week Dr. Yeadon was asked:

“we are basing a government policy, an economic policy, a civil liberties policy, in terms of limiting people to six people in a meeting…all based on, what may well be, completely fake data on this coronavirus?”

Dr. Yeadon answered with a simple “yes.”

Even more significantly, even if all positives were to be correct, Dr. Yeadon said that given the “shape” of all important indicators in a worldwide pandemic, such as hospitalizations, ICU utilization, and deaths, “the pandemic is fundamentally over.”

Yeadon said in the interview:

“Were it not for the test data that you get from the TV all the time, you would rightly conclude that the pandemic was over, as nothing much has happened. Of course people go to the hospital, moving into the autumn flu season…but there is no science to suggest a second wave should happen.”

In a paper published this month, which was co-authored by Yeadon and two of his colleagues, “How Likely is a Second Wave?”, the scientists write:

“It has widely been observed that in all heavily infected countries in Europe and several of the US states likewise, that the shape of the daily deaths vs. time curves is similar to ours in the UK. Many of these curves are not just similar, but almost super imposable.”

In the data for UK, Sweden, the US, and the world, it can be seen that in all cases, deaths were on the rise in March through mid or late April, then began tapering off in a smooth slope which flattened around the end of June and continues to today. The case rates however, based on testing, rise and swing upwards and downwards wildly.

Media messaging in the US is already ramping up expectations of a “second wave.”


Survival Rate of COVID Now Estimated to be 99.8%, Similar to Flu, Prior T-Cell Immunity

The survival rate of COVID-19 has been upgraded since May to 99.8% of infections. This comes close to ordinary flu, the survival rate of which is 99.9%. Although COVID can have serious after-effects, so can flu or any respiratory illness. The present survival rate is far higher than initial grim guesses in March and April, cited by Dr. Anthony Fauci, of 94%, or 20 to 30 times deadlier. The Infection Fatality Rate (IFR) value accepted by Yeadon et al in the paper is .26%. The survival rate of a disease is 100% minus the IFR.

Dr. Yeadon pointed out that the “novel” COVID-19 contagion is novel only in the sense that it is a new type of coronavirus. But, he said, there are presently four strains which circulate freely throughout the population, most often linked to the common cold.

In the scientific paper, Yeadon et al write:

“There are at least four well characterised family members (229E, NL63, OC43 and HKU1) which are endemic and cause some of the common colds we experience, especially in winter. They all have striking sequence similarity to the new coronavirus.”

The scientists argue that much of the population already has, if not antibodies to COVID, some level of “T-cell” immunity from exposure to other related coronaviruses, which have been circulating long before COVID-19.

The scientists write:

“A major component our immune systems is the group of white blood cells called T-cells whose job it is to memorise a short piece of whatever virus we were infected with so the right cell types can multiply rapidly and protect us if we get a related infection. Responses to COVID-19 have been shown in dozens of blood samples taken from donors before the new virus arrived.”

Introducing the idea that some prior immunity to COVID-19 already existed, the authors of “How Likely is a Second Wave?” write:

“It is now established that at least 30% of our population already had immunological recognition of this new virus, before it even arrived…COVID-19 is new, but coronaviruses are not.”

They go on to say that, because of this prior resistance, only 15-25% of a population being infected may be sufficient to reach herd immunity:

“…epidemiological studies show that, with the extent of prior immunity that we can now reasonably assume to be the case, only 15-25% of the population being infected is sufficient to bring the spread of the virus to a halt…”

In the US, accepting a death toll of 200,000, and a survival rate of 99.8%, this would mean for every person who has died, there would be about 400 people who had been infected, and lived. This would translate to around 80 million Americans, or 27% of the population. This touches Yeadon’s and his colleagues’ threshold for herd immunity.

The authors say:

“current literature finds that between 20% and 50% of the population display this pre-pandemic T-cell responsiveness, meaning we could adopt an initially susceptible population value from 80% to 50%. The lower the real initial susceptibility, the more secure we are in our contention that a herd immunity threshold (HIT) has been reached.”


Masthead for "Lockdown" publisher of "How Likely is a Second Wave?"
Masthead for “Lockdown” publisher of “How Likely is a Second Wave?” | Source

The False Positive Second Wave

Of the PCR test, the prevalent COVID test used around the world, the authors write:

“more than half of the positives are likely to be false, potentially all of them.”

The authors explain that what the PCR test actually measures is “simply the presence of partial RNA sequences present in the intact virus,” which could be a piece of dead virus which cannot make the subject sick, and cannot be transmitted, and cannot make anyone else sick.

“…a true positive does not necessarily indicate the presence of viable virus. In limited studies to date, many researchers have shown that some subjects remain PCR-positive long after the ability to culture virus from swabs has disappeared. We term this a ‘cold positive’ (to distinguish it from a ‘hot positive’, someone actually infected with intact virus). The key point about ‘cold positives’ is that they are not ill, not symptomatic, not going to become symptomatic and, furthermore, are unable to infect others.”

Overall, Dr. Yeadon builds the case that any “second wave” of COVID, and any government case for lockdowns, given the well-known principles of epidemiology, will be entirely manufactured.

In Boston this month, a lab suspended doing coronavirus testing after 400 false positives were discovered.

An analysis of PCR-based tests at medical website states:

“data on PCR-based tests for similar viruses show that PCR-based testing produces enough false positive results to make positive results highly unreliable over a broad range of real-world scenarios.”

University of Oxford Professor Carl Heneghan, Director of Oxford’s Centre for Evidence-Based Medicine, writes in a July article “How Many COVID Diagnoses Are False Positives?”:

“going off current testing practices and results, Covid-19 might never be shown to disappear.”

Professor Heneghan’s scientific article on the topic is “Virological characterization of COVID-19 patients that test re-positive for SARS-CoV-2 by RT-PCR.”

Of course, the most famous incidence of PCR test unreliability was when the President of Tanzania revealed to the world that he had covertly sent samples from a goat, a sheep, and a pawpaw fruit to a COVID testing lab. They all came back positive for COVID.

Made in China

In August, the government of Sweden discovered 3700 false COVID positives from test kits made by China’s BGI Genomics. The kits were approved in March by the FDA for use in the US.

Second Waves of Coronaviruses Not Normal

Dr. Yeadon challenged the idea that all pandemics take place in subsequent waves, citing two other coronavirus outbreaks, the SARS virus in 2003, and MERS in 2012. What may seem like two waves can actually be two single waves occurring in different geographical regions. They say data gathered from the relatively recent SARS 2003 and the MERS outbreaks support their contention.

In the case of the MERS:

“it is actually multiple single waves affecting geographically distinct populations at different times as the disease spreads. In this case the first major peak was seen in Saudi Arabia with a second peak some months later in the Republic of Korea. Analysed individually, each area followed a typical single event…”

In the interview, when questioned about the Spanish Flu epidemic of 1918, which came in successive waves during World War I, Yeadon pointed out that this was an entirely different kind of virus, not in the coronavirus family. Others have blamed general early century malnutrition and unsanitary conditions. World War I soldiers, hard hit, lived in cold mud and conditions the worst imaginable for immune resistance.

Saudi and Korea Waves of MERS Coronavirus
Saudi and Korea Waves of MERS Coronavirus

Lockdowns Don’t Work

Another argument made by Yeadon et al in their September paper is that there has been no difference in outcomes related to lockdowns.

They say:

“The shape of the deaths vs. time curve implies a natural process and not one resulting mainly from human interventions…Famously, Sweden has adopted an almost laissez faire approach, with qualified advice given, but no generalised lockdowns. Yet its profile and that of the UK’s is very similar.”

Mild-Mannered Yeadon Demolishes Man Who Started It All, Professor Neil Ferguson

The former Pfizer executive and scientist singles out one former colleague for withering rebuke for his role in the pandemic, Professor Neil Ferguson. Ferguson taught at Imperial College while Yeadon was affiliated. Ferguson’s computer model provided the rationale for governments to launch draconian orders which turned free societies into virtual prisons overnight. Over what is now estimated by the CDC to be a 99.8% survival rate virus.

Dr. Yeadon said in the interview that “no serious scientist gives any validity” to Ferguson’s model.

Speaking with thinly-veiled contempt for Ferguson, Dr. Yeadon took special pains to point out to his interviewer:

“It’s important that you know most scientists don’t accept that it [Ferguson’s model] was even faintly right…but the government is still wedded to the model.”

Yeadon joins other scientists in castigating governments for following Ferguson’s model, the assumptions of which all worldwide lockdowns are based on. One of these scientists is Dr. Johan Giesecke, former chief scientist for the European Center for Disease Control and Prevention, who called Ferguson’s model “the most influential scientific paper” in memory, and also “one of the most wrong.”

It was Ferguson’s model which held that “mitigation” measures were necessary, i.e. social distancing and business closures, in order to prevent, for example, over 2.2 million people dying from COVID in the US.

Ferguson predicted that Sweden would pay a terrible price for no lockdown, with 40,000 COVID deaths by May 1, and 100,000 by June. Sweden’s death count is under 6,000. The Swedish government says this coincides to a mild flu season. Although initially higher, Sweden now has a lower death rate per-capita than the US, which it achieved without the terrific economic damage still ongoing in the US. Sweden never closed restaurants, bars, sports, most schools, or movie theaters. The government never ordered people to wear masks.

Dr. Yeadon speaks bitterly of the lives lost as a result of lockdown policies, and of the “savable” countless lives which will be further lost, from important surgeries and other healthcare deferred, should lockdowns be reimposed, .

Yeadon is a successful entrepreneur, the founder of a biotech company which was acquired by Novartis, another pharmaceutical giant. Yeadon’s unit at Pfizer was the Asthma and Respiratory Research Unit. (Yeadon, partial list of publications.)

Sweden During International "Lockdowns"
Sweden During International “Lockdowns”

Why is All This Happening? US Congressman Says He is Convinced of “Government Plan” to Continue Lockdowns Until a Mandatory Vaccine. Conspiracy Theories?

The list of news items grows which reflects unfavorably upon the narrative being played out on the major television networks, of a mysterious, “novel” virus which has been controlled only by an unprecedented assault on individual rights and liberties, now ready to pounce again, on already suffering populations with no choice but to submit to further government orders.

Governors have quietly extended their powers indefinitely by shifting the goalpost, without saying so, from “flattening the curve” to ease the strain on hospitals, to “no new cases.” From “pandemic,” to “case-demic.”

In Germany, an organization of 500 German doctors and scientists has formed, who say that government response to the COVID virus has been vastly out of proportion to the actual severity of the disease.

Evidence of chicanery mounts. Both the CDC, and US Coronavirus Task Force headed by Dr. Deborah Birx, are candid that the definition of death-by-COVID has been flexible, and that the rules favor calling it COVID whenever possible. This opens the possibility of a vastly inflated death count. In New York, Governor Andrew Cuomo’s administration is under federal investigation for all but signing the death warrants for thousands of nursing home elderly, when the state sent COVID patients into the nursing homes, over the helpless objections of nursing home executives and staff.

Why are the major media ignoring what would seem to be an eminently newsworthy item, an industry rockstar like Yeadon, calling out the biggest guns in the public health world? Would not the Sunday talk shows, the Chris Wallaces and Meet the Press, want to grill such a man for record audiences?

Here the talk may turn to dark agendas, and not just mere incompetence, obtuseness, and stupidity.

One opinion was put forth by US Representative Thomas Massie (R-KY) when he said on the Tom Woods Show on August 16th:

“The secret the government is keeping from you is that they plan to keep us shut down until there is some kind of vaccine, and then whether it’s compulsory at the federal level, or the state level, or maybe they persuade your employers though another PPP program that you won’t qualify for unless you make your employees get the vaccine, I think that’s their plan. Somebody convince me that’s not their plan, because there is no logical ending to this other than that.”

Another theory is that the COVID crisis is being used consolidate never-before-imaged levels of control over individuals and society by elites. This is put forth by the nephew of the slain president, John F. Kennedy Jr., son of also-assassinated Bobby Kennedy. In a speech at a massive anti-lockdown, anti-mandatory COVID vaccination rally in Germany, Bobby Jr. warned of the existence of a:

“bio-security agenda, the rise of the authoritarian surveillance state and the Big Pharma sponsored coup d’etat against liberal democracy…The pandemic is a crisis of convenience for the elite who are dictating these policies,”

In a lawsuit, Kennedy Jr.’s medical witnesses warn that mandatory flu shots may make many children more susceptible to COVID.

The warnings of dire intentions of Kennedy’s “elite” are coming from more mainstream sources. Dr. Joseph Mercola, of the highly trusted, mega-traffic medical information site, has penned a careful review of one doctor’s claims of genetics-altering vaccines coming our way.

And it does not assuage fears that a defense establishment website, Defense One, reports that permanent under-the skin biochips, injectable by the same syringe that holds a vaccine, may soon be approved by the FDA. It does not help the anti-conspiracy theory cause that, according to Newsweek, Dr. Anthony Fauci actually did give NIH funding to the Chinese Wuhan lab, for bat coronavirus research so dangerous it was opposed on record by 200 scientists, and banned in the US.

In 1957, a pandemic hit, the H2N2 Asian Flu with a .7% Infection Fatality Rate, which killed as many people per capita in the US as the COVID has claimed now. There was never a single mention of it in the news at the time, never mind the extraordinary upheaval that we see now. In 1968 the Hong Kong Flu hit the US (.5% IFR,) taking 100,000 people when the US had a markedly lower population. Not single alarm was raised, not a single store closed nor even a network news story. The following summer the largest gathering in US history took place, Woodstock.

Mass hysteria is never accidental, but benefits someone. The only question left to answer is, whom?

Dr. Mike Yeadon Interview

August Protest in Berlin Against Lockdown, and Against Mandatory COVID Vaccination
August Protest in Berlin Against Lockdown, and Against Mandatory COVID Vaccination | Source


Another COVID vaccine using aborted baby cell line pauses trials after participant’s ‘unexplained illness’

This is the second time that trials for a coronavirus vaccine using a cell line developed from tissue from an aborted baby have been halted due to a serious medical concern. 

By Patrick Delaney,

NEW BRUNSWICK, NJ, October 14, 2020 (LifeSiteNews) — Clinical trials for one of the leading potential coronavirus vaccines, which uses cell lines from an aborted baby, have been temporarily paused due to a serious medical complication in one of its participants.

Johnson & Johnson (J&J) released a statement on behalf of their pharmaceutical division Janssen Monday announcing they “have temporarily paused further dosing in all our COVID-19 vaccine candidate clinical trials” due to the development of an “unexplained illness” in one individual.

This pause effects all trials of the J&J vaccine including Janssen’s large-scale Phase 3 clinical trial which began on September 22 and anticipates the enrollment of 60,000 volunteers and 215 research sites.

Though the specific participant’s illness has not been released, it is being evaluated by an “independent Data Safety Monitoring Board” as well as the corporation’s “internal clinical and safety physicians.”

The J&J statement insists that such adverse events “are an expected part of any clinical study, especially large studies” and they have “prespecified guidelines” which provide protocols for pausing such trials when they face a “serious adverse event.”

However, the halting of these clinical trials occurs with a background of concerns raised among experts regarding the potential risks of rushing coronavirus vaccines to the end user in a matter of months, a process which would normally require years to achieve.

Due to the tight timelines required by the Trump Administration’s Operation Warp Speed, the Food and Drug Administration has permitted these potential vaccines to be directly tested on humans without first completing the necessary animal testing to ensure safety and efficacy.

Further, this particular vaccine from J&J utilizes the human fetal cell line PER.C6 for its development. The PER.C6 fetal cell line was derived from retinal tissue taken from an 18-week-old baby boy who was aborted in the Netherlands in 1985 and was later converted into a fetal cell line in 1995.

Dr. Alex van der Eb, who developed the PER. C6 cell line, told FDA hearings in 2001 that the cell line was developed from retinal tissue from an 18 week old preborn baby.

“I isolated retina from a fetus, from a healthy fetus as far as could be seen, of 18 weeks old. There was nothing special with a family history or the pregnancy was completely normal up to the 18 weeks, and it turned out to be a socially indicated abortus – abortus provocatus, and that was simply because the woman wanted to get rid of the fetus…what was written down was unknown father, and that was, in fact, the reason why the abortion was requested.”

This is the second time that trials for a coronavirus vaccine using a cell line developed from tissue from an aborted baby have been halted due to a serious medical concern. Last month AstraZeneca, which is using the HEK 293 cell line, announced a “voluntary pause of vaccination across all trials” due to what the New York Times reported from their sources to be “a diagnosis of transverse myelitis, an inflammatory syndrome that affects the spinal cord and is often sparked by viral infections.” Though the studies in the U.K. have now resumed, according to The Wall Street Journal, they remain “on hold” in the U.S.

Between March and August of this year, the Trump Administration’s Department of Health and Human Services announced the granting of almost $1.5 billion to Johnson & Johnson for the development, testing, manufacturing, and delivery of 100 million doses of this vaccine with the option to purchase more.




Cobra Update 10-14-20… “Final Battle Update”

This post was preceded by the “Final Battle” post (which I did not post here). Much is occurring right now and this Cobra post reflects that. For myself, I’m staying in the Light, getting plenty of rest, and drinking as much Mayan Mocha as my Higher Self asks for!

“Galactic Confederation and Resistance forces are making good progress in eliminating the Draco fleet and the Illuminati Breakaway Complex (IBC). The vast majority of the Draco ships and also the majority of negative Secret Space Programs ships have been cleared already, with very few remaining in the Low Earth Orbit. Many of the Dracos are fleeing the Draco fleet and trying to hide in underground bases, where they are cleared anyway a few days later.

“The Resistance is clearing the underground bases with full force, with Neu Berlin and most other Antarctic underground bases already liberated. Positive Military sources with no access to Resistance intel are reporting unusual seismic activity in Antarctica.

“The Light Forces have also begun the full force operation of clearing the Chimera fleet that was until now hidden in quantum superposition state in sublunar space. They have already managed to clear the majority of Chimera forces from sublunar space and now most of the Chimera fleet is gathered in Low Earth Orbit.

“Chimera beings were once highly evolved angelic beings who chose to subject themselves to controlled toplet bombs explosion experiments long time ago in the galactic past. This, and numerous genetic experiments has mutated them into spider beings of unimaginable darkness… Soon, they will all be finally dealt with.

“The main problem right now on the surface are the engineered covid lockdowns, especially in Australia and Europe:.. These lockdowns are being implemented despite the fact that now even senior WHO officials are speaking against them… it is still very important for as many people as possible to join our daily anti-lockdown meditation

“Since the Resistance has destroyed in spring of this year all advanced biochips that were meant to be put into the covid vaccine, now DARPA is developing a cruder version of vaccine biochips… To counteract all this, Saint Germain is now sending strong energies to empower the implementation of the Constitution of the United States…”


Final Battle Update

Galactic Confederation and Resistance forces are making good progress in eliminating the Draco fleet and the Illuminati Breakaway Complex (IBC). The vast majority of the Draco ships and also the majority of negative Secret Space Programs ships have been cleared already, with very few remaining in the Low Earth Orbit. Many of the Dracos are fleeing the Draco fleet and trying to hide in underground bases, where they are cleared anyway a few days later.

IMAGE (Mjolnir)

The Resistance is clearing the underground bases with full force, with Neu Berlin and most other Antarctic underground bases already liberated.

Positive Military sources with no access to Resistance intel are reporting unusual seismic activity in Antarctica. Those military sources are also reporting evacuation of surface US, Russian, Chinese and Argentinian military bases in Antarctica for unknown reasons.

The Light Forces have also begun the full force operation of clearing the Chimera fleet that was until now hidden in quantum superposition state in sublunar space. They have already managed to clear the majority of Chimera forces from sublunar space and now most of the Chimera fleet is gathered in Low Earth Orbit. Draco military commanders are surrendering all their highly advanced technology to the Chimera forces just before they get cleared by the Galactic Confederation. Draco military high command is now in a state of panic, smelling defeat.

IMAGE (Yoda saying)

Chimera fleet is using the so called quantum black goo as their defense weapon against the progress of the Light Forces. Quantum black goo is simply compressed form of quantum primary anomaly that has been exposed to extreme entropy and is now being released by the Chimera in Low Earth Orbit and is being very effectively cleared by the Light Forces. Yet, it still does contribute to the overall primary anomaly around the planet and to general feeling of doom and gloom which surrounds the Earth:

Chimera beings were once highly evolved angelic beings who chose to subject themselves to controlled toplet bombs explosion experiments long time ago in the galactic past. This, and numerous genetic experiments has mutated them into spider beings of unimaginable darkness:

Soon, they will all be finally dealt with.

Nothing can be said yet about the operations of the Light Forces on the surface. The probability of real Draco fleet invasion on the surface is now less than 1%, probability of fake alien invasion less than 5%, probability of China-USA war about 7%, probability of USA breakup around 20% and probability of civil war in USA at 27%.

The main problem right now on the surface are the engineered covid lockdowns, especially in Australia and Europe:

These lockdowns are being implemented despite the fact that now even senior WHO officials are speaking against them:

Therefore it is still very important for as many people as possible to join our daily anti-lockdown meditation:

More and more people are aware that the official pseudo scientific narrative of covid lockdowns and masks is crumbling:

And real scientific debate is gone:

Because there is a deeper, more sinister agenda of global control:

And of financial gain from confirmed covid cases:

Where is the compassion?

Where is the beauty of life?

Since the Resistance has destroyed in spring of this year all advanced biochips that were meant to be put into the covid vaccine, now DARPA is developing a cruder version of vaccine biochips:

The dark forces are also working on spreadable bioweapon vaccine:

IMAGE (St. Germain)

To counteract all this, Saint Germain is now sending strong energies to empower the implementation of the Constitution of the United States:

The Constitution is a legal document that forms the legal basis for the creation of New Atlantis before the Galactic Codex can be implemented.

Saint Germain was deeply involved in the creation of the United States and in the creation of the Declaration of Independence.

Both Constitution of the United States and Declaration of Independence are legal documents that will have important role in the events which are about to occur in the United States in the next few months and which will have global impact.

Our Flower of Life meditations are already manifesting into the physical:

Beauty of the universe is being revealed:

With music of the spheres from the Galactic Center:

We are now in the midst of the Final Battle:

We remember our past:

And envision our future.

The best is yet to come:

Victory of the Light!

x22Report 10-15-20 VIDEO… “Welcome to 1984, Sometimes you must show the People, FCC Takes Aim” [a Bitchute video]

Here is an x22 from today (well, yesterday). I’m posting, in part, to show that x22 Dave may be reached via Bitchute, as well as his own website.

Please also note that, because of x22’s recent “YouTube banishment”, Dave has set up a private server to store and share his videos, without the “danger” of them being taken down by YouTube. It is available via paid subscription at (quite inexpensive, at $29.99/year, $2.99/month). I have subscribed to this, as I love his news presentations and information.

Published 10-15-20
The [DS]/MSM are now showing their true colors, they are no longer hiding in the shadows, the are censoring where everyone can see.

The patriots are releasing everything they have on Hunter Biden, they are showing the public the truth and the [DS] is doing everything in their power to stop it. This will not work, sometimes you must show the people the truth, the FCC is now taking aim, tick tock.

Alternative channels for x22Report:

Santa Surfing 10-15-20 VIDEOs… “Angel Anon Updates! Get Stocked up! Internet MAY go down! Get ready please!” (plus one more)

These are a couple of short videos that talk briefly about the “banning”. She mentions an anon she communicates with recommending “stock up”. My response to that is “use one’s Higher Discernment to decide what to do or not do”.

I’ve heard that phrase “Get Stocked Up” many many many many many many many many many many many many times, but oftentimes there’s been nothing happened. However, having lived on the islands (possible loss of supplies from ships) and in the MidWest (who the h— knows when the next 25.356″ snowfall is going to hit) to continually stock up for emergencies.

Anyway, I say, “Hold the Light and all will be made Right”.


(Check This Out!!) Was The President not on land when this last video was made??

Posted by John E. Jordan on Sunday, October 4, 2020

How Nitric Oxide Combats COVID-19

I’ve written many articles reviewing a wide variety of therapies demonstrated or hypothesized to have a positive impact on SARS-CoV-2 infection and COVID-19 disease progression. Now, we can add nitric oxide (NO) to the list — not to be confused with nitrous oxide (N2O, a sedative often referred to as laughing gas). According to Åke Lundkvist, a professor at Uppsala University who led the study1 in question:2

“To our knowledge, nitric oxide is the only substance shown so far to have a direct effect on SARS-CoV-2. Until we get a vaccine that works, our hope is that inhalation of NO might be an effective form of treatment. The dosage and timing of starting treatment probably play an important part in the outcome, and now needs to be explored as soon as possible.”

What Is Nitric Oxide?

Nitric oxide (NO) is a soluble gas continually produced from the amino acid L-arginine inside your cells. While NO is a free radical, it’s also an important biological signaling molecule that supports normal endothelial function and protects your mitochondria — the little “power stations” in your cells that produce a majority of your body’s energy in the form of ATP.

It’s stored in the lining of your endothelium (blood vessels), and can be triggered either through exercise or dietary means. NO is a potent vasodilator, helping relax and widen the diameter of your blood vessels.

Healthy blood flow in turn allows for efficient oxygenation of tissues and organs, and aids in the removal of waste and carbon dioxide. Importantly, NO infuses into areas that are hypoxic, meaning in need of oxygen, and both your heart and brain3,4 are heavy oxygen users. NO also:

Improves your immune function, making your body better equipped to fight off foreign pathogens

Has powerful antibacterial potential

Protects your mitochondrial health

Helps maintain physiological homeostasis — For example, in your gut, NO regulates mucosal blood flow, intestinal motility and the thickness of mucus

Plays an important role in the homeostasis of reactive oxygen species, which can have a significant impact on metabolic pathways5

Helps suppress inflammation

Promotes angiogenesis, the formation of new, healthy blood vessels6

Helps improve your physical fitness — For example, raw beets have been shown to boost stamina during exercise by as much as 16% as a result of the increase in NO production7

Improves brain neuroplasticity by improving oxygenation of the somatomotor cortex, a brain area that is often affected in the early stages of dementia8,9

Helps reverse metabolic syndrome10 and has antidiabetic effects11,12

NO Effectively Inhibits SARS-CoV-2 Replication

As mentioned, NO is known to have broad-spectrum antimicrobial effects, and Swedish researchers have now demonstrated that NO effectively inhibits the replication of SARS-CoV-2 in vitro by targeting the SARS-CoV-2 main protease. The study13 in question was published in the October 2020 issue of Redox Biology. As explained in various sections of this paper:14

“Nitric oxide (NO) is a broad-spectrum antimicrobial and a potent vasodilator that has proved to be effective in reducing SARS-CoV replication and hypoxia in patients with severe acute respiratory syndrome …

NO has been demonstrated as an effective antiviral against SARS-CoV in vitro and in vivo by inhalation in very low concentrations in a small clinical trial.

Furthermore, inhaled NO improved arterial oxygenation in hypoxemic patients by redistributing blood flow in the lung to better ventilated regions, and counteracted blood clotting, both effects being of importance for COVID-19 patients.

The role of NO-inhalation in the prevention and treatment of COVID-19 has been proposed, but no clinical data has yet been reported. In the present study the antiviral effect of NO on SARS-CoV-2 infected cells was tested in vitro …

The NO-donor S-nitroso-N-acetylpenicillamine (SNAP) had a dose dependent inhibitory effect on SARS-CoV-2 replication … SNAP (NO donor), but not NAP (NO-lacking version of SNAP) showed a dose dependent reduction of SARS-CoV-2 viral RNA copy numbers, which proves that NO has an antiviral effect against SARS-CoV-2 and probably in the similar manner as previously described for SARS-CoV and other viruses …

Although the viral replication was not completely abolished (at 200 ?M and 400 ?M), SNAP delayed or completely prevented the development of viral cytopathic effect in treated cells, and the observed protective effect correlated with the level of inhibition of the viral replication.”

The image below compares and contrasts the cytopathic effects over time (24-hour intervals) between cells treated with SNAP (a NO donor) at 200 ?M and 400 ?M, and untreated controls. The cells are magnified 100 times.

cytopathic effects over time

SARS-CoV-2 Main Protease Is an Attractive Drug Candidate

The SARS-CoV-2 main protease is a key enzyme in the virus’ life cycle,15 which makes it an attractive target for drug development.16 As explained in one Science paper,17 the SARS-CoV-2 main protease enzyme “cuts the polyproteins translated from viral RNA to yield functional viral proteins.”

By targeting this enzyme, researchers believe you can effectively combat SARS-CoV-2, and that is precisely what NO does. According to the Swedish researchers:18

Based on this study and previous studies on SARS-CoV in vitro, and in a small clinical trial, we conclude that NO may be applied for clinical use in the treatment of COVID-19 and other human coronavirus infections.”

How to Increase NO Production Naturally

While the Swedish researchers suggest using NO inhalation therapy — which is already used for conditions such as hypoxic respiratory failure in adults19 and respiratory failure in neonates20 — you could also boost your resilience against the virus by implementing lifestyle strategies that increase your natural NO production.

For clarity, these strategies would not be of immediate help if you come down with a SARS-CoV-2 infection. Rather, by increasing your body’s production of NO on a regular basis, the virus may be less likely to gain a foothold if you’re exposed to it. That said, three strategies that will increase NO production in your body include:

  1. Blood flow restriction training (BFR)21
  2. Getting sensible sun exposure on large portions of your body, as NO is released into your bloodstream when sunlight hits your skin22,23
  3. Eating nitrate-rich plant foods24,25,26 such as arugula and red beets. NO production can be further magnified by combining these foods with probiotics27

BFR Boosts Vascular Function by Increasing NO

To give you some more details about these strategies, BFR has been shown to improve your vascular function, and one of the ways by which it does this is by increasing NO production. As explained in a 2012 study published in the International Journal of Vascular Medicine:28

“… after several minutes of arterial cuff occlusion at proximal or distal portion in any artery, for example, brachial and popliteal artery, immediate cuff deflation can lead to increase shear stress induced by reactive hyperemia and activate endothelial nitric oxide (NO) synthase (eNOS).

This activation leads to a shear-stress-mediated augmented NO production in endothelial cells … NO bioavailability in the endothelial cell … is an important factor and predictor in protecting against cardiovascular disease.”

The local muscle hypoxia brought on by BFR exercise also significantly increases vascular endothelial growth factor (VEGF), which act like “fertilizer” for your blood vessels. The medical term for this development of new blood vessels is angiogenesis. Angiogenesis, in turn, enhances NO bioavailability.

The following graph illustrates the vascular changes that occur in response to BFR. To learn more about BFR, including how to perform it properly, see “What You Need to Know About Blood Flow Restriction Training.”

vascular changes that occur in response to BFR

Whole Body UVA Irradiation Triggers NO Release

Next up: Sun exposure. It doesn’t get any easier than this, really. All you need to do is expose as much skin as possible to bright sunlight. As always, you’ll want to make sure you don’t stay out too long. Sunburn is counterproductive as it will only harm your skin. Once your skin turns the lightest shade of pink, move into the shade or put on clothing and a hat.

Ultraviolet A (UVA) and the near-infrared light spectrum both increase NO, so you’re getting that benefit from both ends of the light spectrum. As explained in a 2009 paper29 in the journal Circulation Research, when you expose your body to sunlight, photolabile NO derivates such as nitrite and S-nitroso thiols decompose and form vasoactive NO. (Photolabile means the compounds are altered or undergo chemical changes in response to light).

Eat a Nitrate-Rich Diet

Lastly, the dietary component. Dietary nitrates are converted into nitrites by oral bacteria during chewing. Once the nitrites are swallowed and come into contact with stomach acid, they get converted into NO. You can find more in-depth details about this conversion in “Top 9 Reasons to Optimize Your NO Production.” Nitrate-rich foods that can boost your NO level include:30,31,32


Red beets / fermented beets



Butter leaf lettuce

Spring greens like mesclun mix


Oak leaf lettuce

Swiss chard

As mentioned, taking a probiotic can optimize the NO production when eating nitrate-rich foods. The reason for this is because gut bacteria are involved in the first step of the NO metabolism chain. Probiotic bacteria such as Lactobacillus reduce nitrate to nitrite, the latter of which becomes a substrate for NO. So, by adding probiotics, you increase the NO substrate, which allows for higher levels of NO to be generated.

Aside from the many benefits already listed, NO has also been shown to improve muscle contractions in your diaphragm, thereby improving breathing. This, beside its antiviral effects, can have a direct benefit for COVID-19.

For the study,33 researchers split old mice into two groups. (For reference, the mice used in the study were 24 months old, which is equivalent to about 70 years of age in humans.) One group was given drinking water that contained sodium nitrate daily for 14 days. The other group was given plain water.

After the study period, they measured the isometric force and peak power of the diaphragm muscles in the mice and found that both significantly increased in the nitrate group. This increase in force and power translated to improved contraction of the diaphragm muscle, which can then improve lung function and breathing.

The increased power in the diaphragm could also help older people clear their lungs more effectively, which may help reduce the risk of developing infections. Your body’s ability to produce NO declines with age, so it’s important to take steps to increase your NO production as you get older. Respiratory muscle function also declines with age, contributing to breathing troubles, impaired airway clearance and a decreased quality of life.

Since nitrates can improve muscle function of the diaphragm, it may help improve the outlook for older populations with respiratory infections like COVID-19. Dietary nitrates also improve oxygen uptake by dilating the blood vessels and allowing more oxygen to be delivered to muscles, like the diaphragm, and other cells.34

How Molecular Hydrogen Impacts NO Production

In conclusion, I’d like to address the detrimental side of NO, and how this plays into COVID-19. As explained by Tyler W. LeBaron in a recent video lecture featured in “How Molecular Hydrogen Can Help Your Immune System,” most of the destruction wrought by SARS-CoV-2 is through reactive oxygen species (ROS) and systemic inflammation.

And, as mentioned earlier, NO is both a free radical and a signaling molecule. As such, it can have either positive or negative effects, depending on its levels and what else is going on.

ROS are molecules that cause oxidative damage. However, they’re not all bad all the time. Neutrophils that produce ROS also produce NO and superoxide. Superoxide helps kill pathogens, but you also don’t want too much of it, so it needs to be regulated. The same goes for NO.

While NO can inhibit viral replication and boost your immune system, you don’t want too much, because as levels of superoxide and NO rise, they combine and form peroxynitrites, which are extremely damaging. Peroxynitrites in turn form hydroxyl radicals, the most cytotoxic ROS.

Normally, when superoxide has done its job, it’s converted by superoxide dismutase into hydrogen peroxide, which in turn is converted into water and oxygen. This process is regulated by a transcription factor called Nrf2/keap1.

When this transcription factor is activated, it triggers your body’s natural antioxidants such as glutathione and catalase. Nrf2 — which is involved in phase 2 detoxification — regulates more than 200 protective proteins and enzymes. The problem is that when ROS is overabundant and out of control, the Nrf2 system is depleted and can no longer regulate the inflammatory process.

Molecular hydrogen (H2 gas) has the ability to activate the Nrf2/keap1 pathway, thereby replenishing your endogenous antioxidants. In so doing, H2 helps regulate and maintain homeostasis in the whole system, preventing the infection from getting out of control and causing cell death.

H2 can also lower excessive NO and superoxide production by downregulating NOX and NOS enzymes. In a scenario such as COVID-19, this would be good, as when these two molecules are excessively elevated they combine to create the pernicious peroxynitrite molecule.

Considering very high levels of NO appear to be part of the COVID-19 disease process in the later stages, it seems NO inhalation therapy might be best suited in the early stages of infection, not the more advanced stages when inflammation is running wild.

As noted by the Front-Line COVID-19 Critical Care (FLCCC) Alliance,35,36 peak viral replication takes place at the earliest signs of symptoms, which include cold/flu-like symptoms, loss of taste and smell, myalgia (muscle pain) and general malaise.

At this time, the focus should be on antiviral therapies — which is what NO inhalation therapy, in this case, could be designated as. As symptoms worsen, viral replication actually diminishes automatically, giving way to immune dysregulation, so at this point, NO might cause more problems than it solves.

Nebulized Hydrogen Peroxide — A Highly Effective Home Remedy

While unrelated to NO, I believe one of the most effective treatment options available is nebulized hydrogen peroxide. This is a home remedy I recommend everyone familiarize themselves with, as in many cases it can improve symptoms within mere hours. It is particularly effective in those who are in the later stages of the illness.

Dr. David Brownstein, who has successfully treated over 100 COVID-19 patients with nebulized hydrogen peroxide, published a case paper37 about this treatment in the July 2020 issue of Science, Public Health Policy and The Law. He also discusses its benefits in a recent interview I did with him.

In my April 2020 article, “Could Hydrogen Peroxide Treat Coronavirus?” I reviewed some of the basic science of how hydrogen peroxide works, as well as some of the studies assessing its therapeutic potential. The most relevant study38 was published in March 2020 in the Journal of Hospital Infection. They studied 0.5% hydrogen peroxide, and found it killed human coronaviruses, including the coronaviruses responsible for SARS and MERS.

Nebulized hydrogen peroxide is extremely safe. Brownstein has used it for 25 years with no ill effects being found. It’s also incredibly inexpensive, and you can administer it at home, without a prescription. In my view, it is one of the absolute best therapies for viral infections like SARS-CoV-2 or even worse respiratory viruses that will likely be unleashed in the future.

I strongly recommend buying a desktop nebulizer. It needs to produce a very fine mist, and desktop versions are stronger than handheld battery operated models. The one I use is the Pari Trek S Compressor Aerosol System with a face mask, (sold separately) not with the supplied mouth piece.

It is important to acquire the equipment and peroxide BEFORE you need it, as the sooner you treat the infection the better your results will be, although the testimonials are unbelievably impressive even in late stage illness. It is not necessary to treat yourself preventively, but only if you are sick or exposed to someone who is.

While I’ve been using a 0.1% dilution, Brownstein uses an even lower concentration of just 0.04%. Neither Brownstein nor I recommend using commercial 3% hydrogen peroxide found in most grocery stores, as it has potentially toxic chemical stabilizers in it. For optimal benefits, use food-grade peroxide and dilute it appropriately, using saline.

hydrogen peroxide dilution chart

To dilute 35% food-grade peroxide into a 0.04% solution, first dilute it down to 3% by mixing 1 part peroxide with 10 parts sterile water, then take 3 cubic centimeters (CCs) of that 3% dilution and add it to a 250CC bag of normal saline. This brings it down to a .04% hydrogen peroxide concentration. In the video above, I go over the basics of how to do nebulized peroxide.

Why Are NAD+ Precursors so Important?

Niacin is a precursor to nicotinamide adenine dinucleotide (NAD+), a vital signaling molecule1 that’s also believed to play an important role in longevity. This is partly due to its role as an essential substrate for sirtuins,2 which are enzymes related to healthy aging, as well as its role in DNA repair.

NAD+ modulates energy production and many enzymes and in so doing controls hundreds of processes in your body including the survival of cells and energy metabolism. NAD+ is influenced on a daily basis by what you eat, exercise levels and more, and also declines with age, leading to changes in metabolism and an increased risk of disease.3

Boosting NAD+ levels may be akin to a fountain of youth, which is where NR comes in. While there are many ways to increase NAD+, including time-restricted eating and exercise while fasting, supplementation with NAD+ precursors may also be useful.

Why Is NR so Beneficial?

There are multiple precursors to NAD+, each with its own physiologic effects. Nicotinamide riboside (NR) is a popular one with several notable benefits over other precursors like niacin (NA) and niacinamide (NAM). NA, for instance, may induce uncomfortable flushing, while NAM may inhibit sirtuin at high doses, both undesirable effects.4

“Therefore, administration of niacin or niacinamide is unlikely to be widely adopted for maintaining health and function with aging,” researchers wrote in Nature Communications.5 NR has also been shown to offer a variety of significant health benefits. Among them:6

Life extension — In yeast, NR elevates NAD+ and increases sirtuin 2 (SIRT2) function.7 It’s through these increases in NAD+ and sirtuin 2 that calorie restriction is believed to help extend lifespan in mice as well.8

Protects against weight gain — NR supplementation in mice increased NAD+ levels and activated SIRT1 and SIRT3, leading to enhanced oxidative metabolism and protecting against high-fat, diet-induced metabolic abnormalities, including obesity.

The researchers concluded, “Our results indicate that the natural vitamin NR could be used as a nutritional supplement to ameliorate metabolic and age-related disorders characterized by defective mitochondrial function.”9

Heart failure — In a mouse study, NR preserved cardiac function in mice with heart failure.10

Brain injury — NAD+ depletion is common in cases of neurodegeneration. In a mouse study, intracortical administration of NR helped protect against central brain injury.11

Noise-induced hearing loss — Administration of NR, even after exposure to loud noise, prevents noise-induced hearing loss by reducing neurite degeneration.12

Liver protection and antidiabetes effects — In prediabetic mice, NR improved glucose tolerance and reduced weight gain and liver damage. It also prevented fatty liver and helped prevent sensory neuropathy. The researchers concluded the results justified testing NR in humans with obesity and Type 2 diabetes.13

Stem cell regeneration — Among mice exposed to radiation, oral NR improved survival and hematopoietic stem cell regeneration—a benefit that wasn’t seen with in mice given NA or NAM.14

Reversal of chemotherapy-induced neuropathy — In rats, oral NR not only promoted resistance to chemotherapeutic neuropathy but also prompted its reversal.15

Reproductive benefits — Female mice and rats given NR had increased lactation and offspring with a number of health advantages, including increased strength, better memory, less anxiety and enhanced body composition and hippocampal neurogenesis as adults.16

NR Is a Superior Choice Among NAD+ Precursors

Because of its unique profile of benefits and low risks, NR has emerged as a popular choice, especially by its discoverer, biochemist Charles Brenner, among the NAD+ precursors. In Scientific Reports, researchers noted:17

“Because NR does not cause flushing or inhibit sirtuins and the genes (NRK1 and NRK2) required for the metabolism of NR to NAD+ are upregulated in conditions of metabolic stress, NR has a particularly strong potential as a distinct vitamin B3 to support human wellness during metabolic stress and aging.”

Further, according to scientists, these things combined make NR a popular choice for boosting NAD+:18

“NR has unique properties that differentiate it from both niacin and nicotinamide. Unlike niacin, NR does not cause flushing — even at high doses, NR has been shown to be safe in human studies at doses as high as 2000mg/day and does not inhibit sirtuins like nicotinamide. In fact, NR has been shown to activate sirtuins in multiple preclinical studies.

Furthermore, a preclinical study published in Nature Communications, demonstrated that when all three forms of vitamin B3 (niacin, nicotinamide, and NR) were tested head-to-head, NR was not only the most effective at increasing NAD? levels, but it was also the most effective at activating sirtuins.”

The Nature Communications study they referred to found, in fact, that single doses of 100, 300 and 1,000?milligrams (mg) of NR produced dose-dependent increases in NAD+ in humans. They also revealed that blood levels of NAD+ can rise as much as 2.7-fold after a single dose of NR.19

The scientists compared NR to a ski lift, citing that it provided a more direct route to increased NAD+ levels than NR or NAM:20

“NA and NAM both reach the top of the mountain (successfully produce NAD?), however, the paths are winding, and the path for NAM includes inefficiencies in the form of obstacles. Traveling these paths takes more time and energy, which ideally, we would like to conserve in efforts to maximize energy production. The path of NR to NAD? is analogous to the ease of using a ski lift to reach the top of a mountain.

It is much more direct, saving both time and energy — ultimately resulting in the greatest increase in cellular energy production. This concept is further supported by both preclinical and clinical research that suggest NR is the most efficient and effective form of vitamin B3 at boosting NAD? levels.”

Why Boosting NAD+ Is Important

As mentioned, the reason why researchers are so excited over NR is because it appears to efficiently and safely boost NAD+, which otherwise declines with age. In animal studies, restoring NAD+ levels in older or diseased individuals promoted better health ad extended life span, which suggests NAD-boosting molecules like NR have the potential to increase resilience, reduce disease and extend healthy lifespan in humans as well.21

As an aside, it may even have usefulness for COVID-19. According to David Sinclair with Harvard Medical School, the elderly tend to have higher levels of NLRP3 inflammasomes, which appear to be key culprits involved in cytokine storms, which can occur in COVID-19 patients. NLRP3 activity also appears to be influenced by NAD+ levels. Sinclair and colleagues explained in the journal Aging:22

“In older individuals, NLRP3 may be poised for hyperactivation by SARS-CoV-2 antigens. NLRP3 activity is under the direct control of sirtuin 2 (SIRT2), a member of the NAD+-dependent sirtuin family of deacetylases. During aging, NAD+ levels decline, reducing the activity of the sirtuins.

Old mice … have decreased glucose tolerance and increased insulin resistance. This decline, exacerbated by COVID-19, might promote hyperactivation of NLRP3 and the trigger [for] cytokine storms in COVID-19 patients.

Maintaining NAD+ levels may therefore alleviate COVID-19 symptoms, a possibility supported by recent data showing that SARS-CoV-2 proteins hyperactivate poly-ADP-ribose polymerases PARP9, -10, -12, and -14 and deplete cellular NAD+. Additionally, NAD+ precursors lower inflammation in human subjects.”

NAD+ May Be Depleted by 50% by Age 60

Research into NAD+ is still in its infancy, but James Clement, author of “The Switch: Ignite Your Metabolism With Intermittent Fasting, Protein Cycling, and Keto,”23 conducted his own research, starting with a clinical trial testing intravenous NAD+ in elderly people, in collaboration with Dr. John Sturges, who has integrated NAD therapy into his private practice.

Clement underwent the treatment himself, which involved an infusion of 1,000 mg of NAD+ per day for six straight days, and found it remarkably effective for tremors he’d had since he was 20 years old. In my interview with Clement, he stated:

“My hands would shake … It was just some neurological problem. It wasn’t the onset of Parkinson’s at 20 years old or anything else that anyone could point to. But surprisingly, within an hour or two of starting the IV infusion, my tremors went away completely, which I had had for the previous 40 years.

I noticed later that evening that I fell asleep and didn’t wake up during the middle of the night … I woke up way earlier than I normally would, completely refreshed and ready to get back to work. This was the same kind of experiences all of our elderly patients were telling us as well. We had several people who had tremors that went away.”

While he believes 1,000 mg may be too much for those who don’t have a severe NAD+ depletion — and is also cost prohibitive, at $1,000 per IV — he noted that many lifestyle factors can reduce your levels, including alcohol consumption.

Aging is another factor and, according to Clement, NAD+ may be depleted by 50% by the time you’re 60 (compared to in your 20s or 30s), and when you’re 70 you may only have 10% of the amount you did when you were younger.

“And then at 80, there’s almost none,” he said, adding that this will seriously impair your body’s ability to repair broken DNA. “You can see how this huge buildup of damaged DNA in every cell of your body is potentially one of the driving forces of these morbidities that you see with aging, heart disease, cancer [and] Alzheimer’s …”

How to Raise Your NAD+ Levels

I think it is best for everyone to make sure that they are getting about 25 mg of niacin per day. This can be done by using, a free online nutrient analyzer, and/or taking a niacin supplement. Ideally it should be about 12.5 mg taken twice a day, which would be unlikely to cause flushing in most everyone.

Once you have done that you could use NR, but I believe NR has several major problems. One is that it is not inexpensive, although it certainly is less costly than using NAD+ directly. However, once you swallow it your liver detoxifies it and adds a methyl group to it so it tends not to form NAD+ as well in tissues outside the liver.

An alternative strategy would be to make a homemade rectal suppository and deliver the dose that way. This bypasses the liver and would supply the NR directly into your bloodstream. If you were to use NR this would be the better way to administer it.

If you’d prefer to avoid supplementation, there are additional strategies that can help. As mentioned, this includes exercise and time-restricted eating. It’s also important to remember that NR supplementation is not a magic potion.

To maximize its effects, you’ll want to use it in conjunction with an overall healthy lifestyle — one that involves optimizing your sleep, limiting EMF exposure, exercising, intermittently fasting and avoiding food for at least three hours before bed, lest your efforts all be in vain.

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